Search for dissertations about: "fibroblast growth factor-2"

Showing result 1 - 5 of 22 swedish dissertations containing the words fibroblast growth factor-2.

  2. 1. Search for Biomarkers in ALS and Parkinson's Disease : Positron Emission Tomography and Cerebrospinal Fluid Studies

    Author : Anders Johansson; Håkan Askmark; Lennart Persson; Uppsala universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; amyotrophic lateral sclerosis; ALS; Parkinson’s disease; cerebrospinal fluid; positron emission tomography; vascular endothelial growth factor; fibroblast growth factor 2; proteomics; Fourier transform ion cyclotron resonance mass spectrometry; deprenyl-D2; PIB; FDG; L-[β11C]-DOPA; Neurology; Neurologi; Neurology; neurologi;

    Abstract : New biomarkers are needed to improve knowledge about pathophysiology, in order to provide earlier correct diagnosis and to follow disease progression of the neurodegenerative diseases amyotrophic lateral sclerosis (ALS) and Parkinson's disease (PD). The aim of this thesis was to find new biomarkers for these diseases. READ MORE

  4. 2. N-Unsubstituted Glucosamine Residues in Heparan Sulfate and Their Potential Relation to Alzheimer's Disease

    Author : Camilla Westling; Ulf Lindahl; Svein Olav Kolset; Uppsala universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; Biochemistry; heparan sulfate; N-unsubstituted glucosamine; Alzheimer s disease; amyloid beta peptide; amyloidosis; 10E4 antibody; fibroblast growth factor 2; Biokemi; Biochemistry; Biokemi;

    Abstract : Heparan sulfate (HS) is a linear polysaccharide, located on the surface and in the extracellular matrix of most cells, that regulates functions of numerous proteins. HS-protein interaction is mainly mediated by sulfate groups found in N-sulfated (NS) regions of the HS, but may also involve rare HS substituents such as N-unsubstituted glucosamine (GlcNH2) residues. READ MORE

  5. 3. The role of VEGF family in angiogenesis, tumor growth and metastasis

    Author : Xiaojuan Yang; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : Tumor growth is dependent on angiogenesis, and cells in tumor tissues produce various angiogenic factors to induce neovascularization. Among tumor-derived angiogenic factors, members of the vascular endothelial growth factor (VEGF) family are most frequently and highly expressed in various solid tumors. READ MORE

  6. 4. Human Endometrial Angiogenesis : An Immunohistochemical Study of the Endometrial Expression of Angiogenic Growth Factors and Their Corresponding Receptors

    Author : Björn Möller; Matts Olovsson; Bo Lindblom; Kristina Gemzell-Danielsson; Uppsala universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Medicine; Human endometrium; angiogenesis; menstrual cycle; endothelial cells; immunohistochemistry; western blot; VEGF; VEGFR; FGF-2; FGFR; EGF; EGFR; levonorgestrel-releasing intrauterine system; Medicin; Dermatology and venerology; clinical genetics; internal medicine; Dermatologi och venerologi; klinisk genetik; invärtesmedicin;

    Abstract : The human endometrium undergoes dramatic changes in morphology and function during the menstrual cycle. Recurrent angiogenesis (the formation of new blood vessels) is of utmost importance for oxygen supply and nourishment of the rapidly growing endometrial tissue. READ MORE

  7. 5. In Search of Prognostic Factors in Grade 2 Gliomas

    Author : Dan Ribom; Tommy Bergenheim; Uppsala universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Neurosciences; low-grade glioma; positron emission tomography; platelet-derived growth factor receptor; mass spectrometry; alpha 2-HS glycoprotein; Neurovetenskap; Neurology; Neurologi; Neurology; Neurologi;

    Abstract : Grade 2 gliomas are malignant brain tumours affecting otherwise healthy adults. Although the long-term prognosis is poor, many patients are well and may have a high quality of life for several years. READ MORE