Search for dissertations about: "fitness cost"

Showing result 1 - 5 of 74 swedish dissertations containing the words fitness cost.

  1. 1. Bacterial Resistance to Antimicrobial Peptides Rates, Mechanisms and Fitness Effects

    University dissertation from Uppsala : Acta Universitatis Upsaliensis

    Author : Maria Pränting; Uppsala universitet.; [2010]
    Keywords : antimicrobial peptides; antibiotic resistance; fitness cost; bacterial evolution; small colony variants; cyclotides; Biologi med inriktning mot mikrobiologi; Biology with specialization in Microbiology; Mikrobiologi; Microbiology;

    Abstract : The rapid emergence of bacterial resistance to antibiotics has necessitated the development of alternative treatment strategies. Antimicrobial peptides (AMPs) are important immune system components that kill microbes rapidly and have broad activity-spectra, making them promising leads for new pharmaceuticals. READ MORE

  2. 2. Multi-Resistance Plasmids Fitness Costs, Dynamics and Evolution

    University dissertation from Uppsala : Acta Universitatis Upsaliensis

    Author : Fredrika Rajer; Uppsala universitet.; [2019]
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; multi-resistance plasmids; evolution; fitness cost; dynamics; escherichia coli; ESBL; gene amplification; β-lactamase inhibitor; Biologi med inriktning mot mikrobiologi; Biology with specialization in Microbiology;

    Abstract : Antibiotic resistance is an escalating problem, not only due to less desirable treatment options and outcome, but also due to the economic burden to health care caused by resistant pathogens. Since the process of developing new antibiotics is slow, we need to carefully consider the usage of the antibiotics still available. READ MORE

  3. 3. The Physiological Cost of Antibiotic Resistance

    University dissertation from Uppsala : Acta Universitatis Upsaliensis

    Author : Mirjana Macvanin; Uppsala universitet.; [2003]
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Microbiology; fusidic acid; fitness cost; protein synthesis; EF-G; ppGpp; RpoS; oxidative stress; heme; Mikrobiologi; MEDICINE Microbiology; immunology; infectious diseases; MEDICIN Mikrobiologi; immunologi; infektionssjukdomar;

    Abstract : Becoming antibiotic resistant is often associated with fitness costs for the resistant bacteria. This is seen as a loss of competitiveness against the antibiotic-sensitive wild-type in an antibiotic-free environment. READ MORE

  4. 4. Experimental Evolution and Fitness Effects of Mutations

    University dissertation from Uppsala : Acta Universitatis Upsaliensis

    Author : Anna Knöppel; Uppsala universitet.; [2016]
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; Experimental evolution; Fitness effects; mutations; S20; fis; ribosome; horizontal gene transfer; adaptation; synonymous mutations; Mikrobiologi; Microbiology;

    Abstract : Bacteria have small, streamlined genomes and evolve rapidly. Their large population sizes allow selection to be the main driver of evolution. With advances in sequencing technologies and precise methods for genetic engineering, many bacteria are excellent models for studying elementary questions in evolutionary biology. READ MORE

  5. 5. Physiology of Cross-Country Skiing : with a special emphasis on the role of the upper body

    University dissertation from Stockholm : US AB

    Author : Hans-Christer Holmberg; Mittuniversitetet.; [2005]
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Arterial O2 saturation; blood flow; conductance; cross-country skiing; double poling; electromyography; ergometer; O2 extraction; force; lung; muscle adaptation; oxygen uptake; oxygen cost; pulmonary gas exchange; training; upper body; INTERDISCIPLINARY RESEARCH AREAS Sports; TVÄRVETENSKAPLIGA FORSKNINGSOMRÅDEN Idrott;

    Abstract : .... READ MORE