Search for dissertations about: "fluorescence cytometry"

Showing result 1 - 5 of 59 swedish dissertations containing the words fluorescence cytometry.

  1. 1. Telomere analysis of normal and neoplastic hematopoietic cells : studies focusing on fluorescence in situ hybridization and flow cytometry

    Author : Magnus Hultdin; Umeå universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Biomedicine; telomere; telomerase; fluorescence in situ hybridization; flow cytometry; flow-FISH; replication timing; chronic lymphocytic leukemia; immunoglobulin gene; prognosis; Biomedicin; Microbiology; Mikrobiologi; Medical Cell Biology; medicinsk cellbiologi;

    Abstract : The telomeres are specialized structures at the end of the chromosomes composed of the repeated DNA sequence (TTAGGG)n and specific proteins bound to the DNA. The telomeres protect the chromosomes from degradation and end to end fusions. READ MORE

  2. 2. Acoustic Forces in Cytometry and Biomedical Applications: Multidimensional Acoustophoresis

    Author : Carl Grenvall; Avdelningen för Biomedicinsk teknik; []
    Keywords : TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; Acoustophoresis; Microfluidics; Ultrasound; Multinode; Cell Sorting; Particle Positioning; Cytometry; Lab-on-a-Chip; µTAS; Binary Separation; Acoustic Barriers; Acoustic Particle Manipulation; Acoustic Standing Waves; Blood Separation; Milk Analysis;

    Abstract : Over the last decades the ongoing work in the fields of Lab-on-a-Chip and Micro-Total-Analysis-Systems has led to the discovery of new or improved ways to handle and analyse small volumes of biofluids and complex biosuspensions. The benefits of working on the microscale include: miniaturization of the analysis systems with less need for large sample volumes; temporal and spatial control of suspended particle/cell positions; low volume sheath flow lamination or mixing; novel separation techniques by using forces inherent to the microscale domain; precise regulation of sample temperatures and rapid analysis with less volumes needed to be processed. READ MORE

  3. 3. Methods and models for 2D and 3D image analysis in microscopy, in particular for the study of muscle cells

    Author : Patrick Karlsson Edlund; Ewert Bengtsson; Joakim Lindblad; Carolina Wählby; Fritz Albregtsen; Uppsala universitet; []
    Keywords : medical image analysis; image segmentation; fluorescence microscopy; cytometry; human skeletal muscle;

    Abstract : Many research questions in biological research lead to numerous microscope images that need to be evaluated. Here digital image cytometry, i.e., quantitative, automated or semi-automated analysis of the images is an important rapidly growing discipline. READ MORE

  4. 4. Cellular Uptake of Amyloid Forming Proteins Related to Neurodegenerative Disease

    Author : Emelie Vilhelmsson Wesén; Chalmers tekniska högskola; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Aβ 1-40 ; flow cytometry; confocal microscopy; SH-SY5Y; fluorescence; Aβ 1-42 ; Alzheimer’s disease; amyloid fibril; α-synuclein; amyloid-β;

    Abstract : Aggregation and deposition of disease-associated protein is a pathological hallmark of several human disorders, including Alzheimer’s disease (AD) and Parkinson’s disease (PD). These diseases are characterized by the formation of amyloid-β (Aβ) and α-synuclein (α-syn) amyloid fibrils, in extracellular and intracellular locations, respectively. READ MORE

  5. 5. Clinical fluorescence cytometry : improvements to preparation methods and instrumentation

    Author : Thomas Heiden; Karolinska Institutet; Karolinska Institutet; []
    Keywords : Fluorescence analysis; flow cytometry; image cytometry; DNA ploidy; proliferation; apoptosis; paraffin-embedded tissues; fresh tissues; S-phase fraction; debris; aggregates; spectral overlap; wavelength switching;

    Abstract : Fluorescence cytometry, which can be carried out by flow or image cytometry (FCM, ICM), provides a highly sensitive and specific tool for quantitative analysis of cell material. It is emerging from being a pure research method and becoming an important adjunct to clinical practice. To better realize its potential, more research is needed. READ MORE