Search for dissertations about: "fluorescence enhancement"

Showing result 1 - 5 of 39 swedish dissertations containing the words fluorescence enhancement.

  1. 1. Development and Use of Optical Sensors in Modern Analytical Chemistry

    Author : Aron Hakonen; Göteborgs universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; Optical sensors; Optodes; Imaging sensors; Fluorescence; pH; Ammonium; Sensing; Nanoparticle enhancement; Plasmonics;

    Abstract : A successful long-term high resolution imaging experiment in marine sediments was performed (17 days within the sample; Paper I). The time correlated calibration procedure was evolved to include parametric sigmoidal and logarithmic functions to provide three of the best performing (optical) pH sensors available up to date (Papers II, III and IV), precision of these sensors were in the 0. READ MORE

  2. 2. Taming the Griffin : Membrane interactions of peripheral and monotopic glycosyltransferases and dynamics of bacterial and plant lipids in bicelles

    Author : Jobst Liebau; Lena Mäler; Charles Sanders; Stockholms universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; membrane; bicelle; lipid; detergent; lipopolysaccharide; glycosyltransferase; WaaG; fluorescence; circular dichroism; NMR; paramagnetic relaxation enhancement; model-free approach; dynamics; Biophysics; biofysik;

    Abstract : Biological membranes form a protective barrier around cells and cellular compartments. A broad range of biochemical processes occur in or at membranes demonstrating that they are not only of structural but also of functional importance. One important class of membrane proteins are membrane-associated glycosyltransferases. READ MORE

  3. 3. Biomarker detection via lab-on-a-chip integrated immunoaffinity approach for fluorescence and mass spectrometry readout

    Author : Asilah Ahmad Tajudin; Avdelningen för Biomedicinsk teknik; []
    Keywords : TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; immunoaffinity; affinity prefractionation; immunoMALDI; solid-phase extraction; protein digestion; ISET; antibody microarray; signal amplification; fluorescence; microfluidics; lab on a chip; separation; acoustophoresis; ultrasound; acoustic radiation force; plasma; proteomics; MALDI mass spectrometry; immunoassay; porous silicon.;

    Abstract : The blood/plasma protein biomarker profile represents the pathological and physiological changes relating to human diseases. However, the plasma proteome reflects a high degree of complexity that results in a challenge for most analytical methods in clinical diagnostics. READ MORE

  4. 4. Conformationally Constrained Nucleosides, Nucleotides and Oligonucleotides : Design, Synthesis and Properties

    Author : Dmytro Honcharenko; Jyoti Chattopadhyaya; Piet Herdewijn; Uppsala universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; Bioorganic chemistry; antisense oligonucleotides; conformationally constrained nucleosides; azetidine; aza-ENA; target affinity; RNase H; exonuclease stability; pyrene-functionalized nucleotides; fluorescence; mismatch discrimination; Bioorganisk kemi; Cell and molecular biology; Cell- och molekylärbiologi;

    Abstract : This thesis is based on six original research publications describing synthesis, structure and physicochemical and biochemical analysis of chemically modified oligonucleotides (ONs) in terms of their potential diagnostic and therapeutic applications. Synthesis of two types of bicyclic conformationally constrained nucleosides, North-East locked 1',2'-azetidine and North locked 2',4'-aza-ENA, is described. READ MORE

  5. 5. Plasmonic Nanostructures for Molecular Spectroscopy

    Author : Björn Brian; Chalmers tekniska högskola; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; SEF; DNA; EBL; Nanoparticles; rhodamine 6G; biosensors; SERS; fluorescence;

    Abstract : This thesis focuses on the fabrication, characterization and utilization of nanostructures for chemical sensing and optical enhancement processes.Noble metal nanostructures can support localized surface plasmon resonances (LSPRs), which amplify the strength of the electromagnetic field close to the structures. READ MORE