Search for dissertations about: "fluorescence in situ hybridization FISH"
Showing result 1 - 5 of 37 swedish dissertations containing the words fluorescence in situ hybridization FISH.
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1. Telomere analysis of normal and neoplastic hematopoietic cells : studies focusing on fluorescence in situ hybridization and flow cytometry
Abstract : The telomeres are specialized structures at the end of the chromosomes composed of the repeated DNA sequence (TTAGGG)n and specific proteins bound to the DNA. The telomeres protect the chromosomes from degradation and end to end fusions. READ MORE
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2. Molecular Cytogenetics in Sporadic Breast Cancer
Abstract : In recent time breast cancer has become the most common form of female cancer in the western world. It has been estimated that the lifetime risk of women falling ill from the disease is 10%. The number of patients diagnosed each year has been increasing steadily since the 1970s. READ MORE
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3. Genetic characterization of non-Hodgkin lymphomas using in situ hybridization
Abstract : Fluorescence in situ hybridization (FISH) has been shown to be a valuable and important technique in cytogenetics, as a complement to traditional banding analysis. This thesis focus on the characterization of chromosomal rearrangements in two hematological neoplasias, myelodysplastic syndrome (MDS) and non-Hodgkin lymphoma (NHL) using FISH. READ MORE
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4. Molecular Characterization of Genomic Amplifications in Pancreatic Cancer
Abstract : Pancreatic cancer includes multiple histologic subtypes that show large differences in their clinical and biological characteristics. Despite this diversity, more than 85% of the neoplasms in the organ are malignant ductal adenocarcinomas, which are the focus of the present thesis. READ MORE
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5. Trisomies in Hematologic Malignancies
Abstract : Acquired clonal chromosome aberrations, closely associated with leukemogenesis, are found in many hematologic malignancies. Although the balanced rearrangements, such as translocations and inversions, are the ones most commonly thought of in the context of leukemias, gains of chromosomes ? e.g.. READ MORE