Search for dissertations about: "fluorescence in-situ hybridization"

Showing result 1 - 5 of 56 swedish dissertations containing the words fluorescence in-situ hybridization.

2. 1. Telomere analysis of normal and neoplastic hematopoietic cells : studies focusing on fluorescence in situ hybridization and flow cytometry

   Author : Magnus Hultdin; Umeå universitet; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Biomedicine; telomere; telomerase; fluorescence in situ hybridization; flow cytometry; flow-FISH; replication timing; chronic lymphocytic leukemia; immunoglobulin gene; prognosis; Biomedicin; Microbiology; Mikrobiologi; Medical Cell Biology; medicinsk cellbiologi;

   Abstract : The telomeres are specialized structures at the end of the chromosomes composed of the repeated DNA sequence (TTAGGG)n and specific proteins bound to the DNA. The telomeres protect the chromosomes from degradation and end to end fusions. READ MORE

4. 2. Genetic characterization of non-Hodgkin lymphomas using in situ hybridization

   Author : Svetlana Lagercrantz; Karolinska Institutet; Karolinska Institutet; []
   Keywords : Myelodysplastic syndrome; non-Hodgkin lymphoma; fluorescencein situ hybridization; LAZ3BCL6 expression; chromosome rearrangements;

   Abstract : Fluorescence in situ hybridization (FISH) has been shown to be a valuable and important technique in cytogenetics, as a complement to traditional banding analysis. This thesis focus on the characterization of chromosomal rearrangements in two hematological neoplasias, myelodysplastic syndrome (MDS) and non-Hodgkin lymphoma (NHL) using FISH. READ MORE

5. 3. Applications of in situ proximity ligation assays for cancer research and diagnostics

   Author : Liza Löf; Masood Kamali-Moghaddam; Ulf Landegren; J.Paul Robinson; Uppsala universitet; []
   Keywords : Cancer; Diagnostics; Research; Prognostics; Method development; Flow cytometry; Drug delivery; Molekylär medicin; Molecular Medicine;

   Abstract : In the field of cancer research and diagnostics it is crucial to have reliable methods for detecting molecules involved in the disease. New and better methods for diagnostics, prognostics and drug delivery therefore remain a permanent aim. READ MORE

6. 4. Genotyping RNA and DNA using padlock probes

   Author : Dan-Oscar Antson; Uppsala universitet; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Genetics; Padlock probe; enzymatic synthesis; PCR; in situ hybridization; RNA-templated DNA ligation; Genetik; Clinical genetics; Klinisk genetik; Medical Genetics; medicinsk genetik;

   Abstract : Novel techniques are needed to investigate the genetic variation revealed in the first draft of the human genome sequence. Padlock probes are recently developed reagents, suitable for detecting single-nucleotide variations of DNA and RNA in situ or in solution. READ MORE

7. 5. Biotechnological treatment of chlorophenol-contaminated water

   Author : Hamid Zilouei; Bioteknik; []
   Keywords : TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; Biotechnology; Bioteknik; kontroll av utsläpp; Miljöteknik; pollution control; Environmental technology; Cell-based biosensor; Fluorescence in situ hybridization; Bacterial community; Two-liquid phase partitioning bioreactor; Photolysis pretreatment; Biomonitoring; Fixed-biofilm reactors; Toxic organic pollutant; Biodegradation;

   Abstract : Widespread presence of toxic and persistent pollutants in the environment, even at low concentrations, causes risks of adverse effects to human health and the ecosystem. Biological methods for treatment of water streams and removal of persistent pollutants are of great interest due to their simplicity, low cost, and mild operational conditions without harmful by-products. READ MORE