Search for dissertations about: "fluorescent markers DNA"
Showing result 1 - 5 of 10 swedish dissertations containing the words fluorescent markers DNA.
-
1. Expanding the alphabet of fluorescent nucleic acid base analogues: Characterization of new members
Abstract : Fluorescence has proven to be a powerful tool for studying structure, dynamics and interactions of biomolecules such as proteins, RNA and DNA. However, since the natural DNA/RNA nucleobases are virtually non-fluorescent, there is a need for developing fluorescent nucleic acid markers. READ MORE
-
2. Applications of Four-Colour Fluorescent Primer Extension Technology for SNP Analysis and Discovery
Abstract : Studies on genetic variation can reveal effects on traits and disease, both in humans and in model organisms. Good technology for the analysis of DNA sequence variations is critical. Currently the development towards assays for large-scale and parallel DNA sequencing and genotyping is progressing rapidly. READ MORE
-
3. Genome mapping of the horse
Abstract : Our ability to map and sequence whole genomes is one of the most important developments in biological science. It will provide us with an unprecedented insight into the genetic background of phenotypic traits, such as disease resistance, reproduction and growth and also makes it feasible to study the processes of genome evolution. READ MORE
-
4. Methods for Analysis of Disease Associated Genomic Sequence Variation
Abstract : In Molecular Medicine a wide range of methods are applied to analyze the genome to find genetic predictors of human disease. Apart from predisposing disease, genetic variations may also serve as genetic markers in the search for factors underlying complex diseases. READ MORE
-
5. The genetics of systemic lupus erythematosus : Mapping of susceptibility loci for human SLE
Abstract : Systemic lupus erythematosus (SLE) is a systemic autoimmune disease affecting organs such as skin, jointsand kidneys. Characteristic for the disease is increased production of autoantibodies, in particular against dsDNA. Previous studies of SLE in mouse models and in humans indicate polygenic inheritance and genetic heterogeneity. READ MORE