Search for dissertations about: "fluoroquinolone"

Showing result 6 - 10 of 20 swedish dissertations containing the word fluoroquinolone.

  2. 6. Chromosomal antibiotic resistance mechanisms in Pseudomonas aeruginosa and Neisseria gonorrhoeae

    Author : Sohidul Islam; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : The progressive increase in fluoroquinolone resistant N. gonorrhoeae and emergence of multiple antibiotic resistant P. aeruginosa are growing concerns among physicians and health policy makers. In N. READ MORE

  4. 7. Relation Between Drug Exposure and Selection of Antibiotic Resistant Bacteria

    Author : Sara K. Olofsson; Otto Cars; Dan I. Andersson; Diarmaid Hughes; George G. Zhanel; Uppsala universitet; []
    Keywords : Microbiology; Pharmacokinetics; Pharmacodynamics; Antibiotic resistance; Selection; Transmission; Mathematical model; Escherichia coli; Mikrobiologi;

    Abstract : The worldwide increase in antibiotic resistance is a concern for public health. When the appropriate antibiotic dosage is determined, the priorities are efficacy and toxicity. The aim of this thesis was to gain knowledge about the most efficient dosing regimens in order to minimize the emergence and selection of antibiotic-resistant mutants. READ MORE

  5. 8. Chemical use in shrimp farming and environmental implications of antibiotic pollution

    Author : Sara Gräslund; Nils Kautsky; Bent Halling-Sørensen; Stockholms universitet; []
    Keywords : ;

    Abstract : Shrimp farming is a highly important industry in southeast Asia. A major threat to profitable shrimp farming is disease outbreaks, which has lead to a situation where a large number of chemicals are used to prevent and treat infections. READ MORE

  6. 9. Computational methods for analysis of fragmented sequence data

    Author : Fredrik Boulund; Göteborgs universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; bioinformatics; metagenomics; proteomics; sequencing; distributed computing; bioinformatics;

    Abstract : Recent developments in genomic and proteomic sequencing technologies have revolutionized research in life sciences, providing new opportunities for the study of biological systems. However, modern sequence data sets are large, diverse, and heavily fragmented, which presents new challenges for their analysis and interpretation. READ MORE

  7. 10. Analysis of large-scale metagenomic data

    Author : Fredrik Boulund; Göteborgs universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; metagenomics; DNA analysis; big data; antibiotic resistance; hidden Markov models; high-performance computing; distributed computing; distributed computing;

    Abstract : The topic of this thesis is the analysis of large data sets of DNA sequence data produced from modern high-throughput DNA sequencing machines. Using such machines to sequence the genetic content of a microbial community produces a metagenome. This thesis comprises three research papers, all connected to the study of large metagenomic data sets. READ MORE