Search for dissertations about: "foam cell formation"

Showing result 1 - 5 of 28 swedish dissertations containing the words foam cell formation.

  2. 1. Transcriptional and post-transcriptional regulation of vascular smooth muscle cell phenotype - Implications for vascular disease states

    Author : Azra Alajbegovic; Molekylär kärlfysiologi; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; Vascular smooth muscle cells VSMC ; cell phenotype; microRNA; Aneurysm; hypertension; Actin polymerization; GATA6; MRTFA; Vascular disease;

    Abstract : As the world population is pushing toward 8 billion, cardiovascular diseases (CVD) remain the leading cause of death worldwide, representing 30% of all global deaths. A large body of work has recognized that smooth muscle cells (SMCs) surrounding the blood vessels play a prominent role in the development and progression of cardiovascular diseases. READ MORE

  4. 2. Lipid storage and secretion. Studies on VLDL assembly and foam cell formation

    Author : Björn Magnusson; Göteborgs universitet; []
    Keywords : ADP-ribosylation factor 1; very low density lipoprotein; lipid droplet; adipocyte differentiation-related protein; hypoxia; foam cell;

    Abstract : This thesis deals with formation of two factors of upmost importance for the development of atherosclerosis: the triglyceride rich very low density lipoproteins 1 (VLDL1) and the lipid loaded macrophages ("foam cells"- characteristic features of the atherosclerotic lesion). Both these processes depend on the cellular accumulation of lipids. READ MORE

  5. 3. Intracellular lipids and inflammatory activity in macrophage foam cells

    Author : Jenny Persson; Kardiovaskulär forskning - immunitet och ateroskleros; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Kardiovaskulära systemet; Cardiovascular system; lipid droplet; cytokine; inflammation; adipophilin; perilipin; atherosclerosis; Macrophage; foam cell;

    Abstract : Cardiovascular disease (CVD) is characterized by lipid accumulation and inflammation in arteries. The disease starts early in life with migration of monocytes into the arterial wall where they engulf entrapped lipoproteins and become macrophage foam cell. READ MORE

  6. 4. Studies on receptors for modified LDL in human monocytes and macrophages : a link between diabetes and atherosclerosis?

    Author : Linda Svensson; Göteborgs universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; atherosclerosis; diabetes CD14; CD36; CD64; fatty acid; flow cytometry; macrophage; monocyte; scavenger receptor;

    Abstract : Type 2 diabetes increases the risk for cardiovascular disease three- to fourfold. Because of the rise in diabetes prevalence there is a need for a better understanding of the link between diabetes and atherosclerosis. READ MORE

  7. 5. Foam Core Materials for High Performance Sandwich Constructions: Preparation, Testing and Properties

    Author : Mikael Danielsson; Chalmers tekniska högskola; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; IPN; core material; low temperature; polyurea; polyethersulfone; gradient structure; foam; PVC; sandwich; waste; fire; smoke; toxicity; mechanical properties; Inter Penetrating Polymer Network; dynamic properties; high temperature;

    Abstract : The basic task for foams used as core materials in sandwich constructions is to separate the skin layers in order to enhance stiffness with little contribution to the total weight. However, modern design in sandwich technology require that core materials contribute to the perfor-mance with specific mechanical and physical properties. READ MORE