Search for dissertations about: "focal brain injury"

Showing result 1 - 5 of 30 swedish dissertations containing the words focal brain injury.

2. 1. Brain Tissue Oxygenation in Traumatic Brain Injury : Experimental and Clinical Studies

   Author : Karlis Purins; Anders Lewén; Per Enblad; Oliver Sakowitz; Uppsala universitet; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Brain tissue oxygenation; Cerebral metabolism; Traumatic brain injury; Cerebral ischemia; Threshold levels; Neurovent-PTO; Microdialysis; Neurosurgery; Neurokirurgi;

   Abstract : Traumatic brain injury (TBI) is a major cause of death and disability. TBI is frequently followed by cerebral ischemia which is a great contributor to secondary brain damage. The main causes of cerebral ischemia are pathophysiological changes in cerebral blood flow and metabolism. READ MORE

4. 2. Clinical Consequences of Axonal Injury in Traumatic Brain Injury

   Author : Sami Abu Hamdeh; Niklas Marklund; Per Enblad; Lars Hillered; Andreas PhD Unterberg MD; Uppsala universitet; []
   Keywords : Traumatic brain injury; diffuse axonal injury; intracranial pressure; magnetic resonance imaging; amyloid-beta; tau; Neurokirurgi; Neurosurgery;

   Abstract : Traumatic brain injury (TBI), mainly caused by road-traffic accidents and falls, is a leading cause of mortality. Survivors often display debilitating motor, sensory and cognitive symptoms, leading to reduced quality of life and a profound economic burden to society. READ MORE

5. 3. Oligodendrocyte pathology following Traumatic Brain Injury : Experimental and clinical studies

   Author : Johanna Flygt; Niklas Marklund; Fredrik Piehl; Uppsala universitet; []
   Keywords : Traumatic brain injury; oligodendrocytes; oligodendrocyte progenitor cells; interleukin 1-β; central fluid percussion injury; Neurokirurgi; Neurosurgery; Neurokirurgi; Neurosurgery;

   Abstract : Traumatic brain injury (TBI) caused by traffic and fall accidents, sports-related injuries and violence commonly results in life-changing disabilities. Cognitive impairments following TBI may be due to disruption of axons, stretched by the acceleration/deceleration forces of the initial impact, and their surrounding myelin in neuronal networks. READ MORE

6. 4. Cognitive Deficits Reflecting Diffuse and Focal Brain Lesions Caused by Slow Growing Brain Tumors - Low-grade Gliomas

   Author : Lena Ek; Ove Almkvist; Anja Smits; Hans Samuelsson; Stockholms universitet; []
   Keywords : SAMHÄLLSVETENSKAP; SOCIAL SCIENCES; Cognition; low-grade glioma; brain tumor; diffuse brain injury; neuropsychological tests; Psychology; Psykologi; Psychology; psykologi;

   Abstract : The overall purpose was to characterize the impact that low-grade glioma (LGG) – a type of slowly growing brain tumor – has on cognitive functions. Paper I was an in-depth analysis of cognitive dysfunction of patients with histological proven LGG. READ MORE

7. 5. Assessment of experimental neurotrauma

   Author : Ying-Lai Huang; Göteborgs universitet; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Impulse noise; diffuse brain injury; focal brain injury; closed head injury; NSE; S-100; GFAP; apoptosis; astrocytosis; glutamate; c-JUN; rotational acceleration; CSF;

   Abstract : Model systems of closed head injury are designed to replicate aspects of traumatic brain injury, ischemia and epilepsy in man. The aim of this thesis was to (1) develop sensitive systems enabling analyses of the biochemical reactions, as reflected by leakage of marker compounds to the cerebrospinal fluid (CSF); and (2) develop and assess a new model for closed head injury and associated dynamic changes in the brain cell. READ MORE