Search for dissertations about: "focal liver lesions"

Showing result 1 - 5 of 6 swedish dissertations containing the words focal liver lesions.

  1. 1. Perfusion computed tomography of the liver

    Author : Katharina Brehmer; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : Background: Perfusion CT (P-CT) is a relatively new imaging technique that permits the visual and quantitative assessment of the micro- and macrocirculation of a target organ and focal lesions. P-CT has shown promising results in the evaluation of hyper-vascular tumors such as hepatocellular carcinoma (HCC). READ MORE

  2. 2. Liver tumour promoting effects by polychlorinated biphenyls

    Author : Marie Haag Grönlund; Karolinska Institutet; Karolinska Institutet; []
    Keywords : tumour promotion; altered hepatic foci; rat liver; PCB; potency; TEF; interactions; antagonism; biologically based cancer growth models; TCDD;

    Abstract : PCBs cause a number of toxic effects and are present in a variety of biological samples including fish, meat and diary products. Cancer is a serious toxic effect by PCBs that has been observed in animal experiments but the knowledge about PCB induced carcinogenicity is still scarce. READ MORE

  3. 3. The attenuation of the P53 response to DNA damage in rodent liver preneoplastic enzyme-altered foci

    Author : Niklas Finnberg; Karolinska Institutet; Karolinska Institutet; []
    Keywords : Enzyme-altered foci; p53; ATM; diethylnitrosamine; phenobarbital; liver; gene dosage;

    Abstract : In connection with life-time bioassays in rodents, the liver is one of the organs most frequently affected. During the carcinogenic process, single preneoplastic hepatocytes develop into hepatocellular adenoma or carcinoma (HCC). READ MORE

  4. 4. Clinical and molecular features of chronic hepatitis C infection and advanced liver disease

    Author : Nogol Rahbin; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : The aim of this thesis was to study molecular and clinical aspects of hepatitis C infection (HCV), especially in patients with advanced liver disease. In the first study we investigated whether the use of a second generation contrast agent in ultrasound (US) examinations can improve detection of hepatocellular carcinoma (HCC) and characterisation of focal liver lesions in 49 HCV-infected patients with liver cirrhosis. READ MORE

  5. 5. Epidemiological, clinical anf pathogenetic studies of acute intermittent porphyria

    Author : Ingemar Bylesjö; Christer Andersson; Pertti Mustajoki; Umeå universitet; []
    Keywords : Medicine; Acute intermittent porphyria; epilepsy; melatonin; diabetes mellitus; white-matter lesions; symptoms; Medicin; Medicine; medicin;

    Abstract : Porphyrias are inherited metabolic disorders characterised by an impairment of heme biosynthesis. Acute intermittent porphyria (AIP) is the most common of the acute porphyrias in Sweden. Acute attacks of AIP are characterised by neuro-psychiatric symptoms, including epileptic seizures. READ MORE