Search for dissertations about: "fold recognition"

Showing result 1 - 5 of 54 swedish dissertations containing the words fold recognition.

  2. 1. Studies of genes involved in regulating flowering time in Arabidopsis

    Author : Maria Svensson; Högskolan i Skövde; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; Arabidopsis thaliana; flowering time; fold recognition; GA biosynthesis; promoter trapping; RNA-binding; T-DNA tagging; Biology; Biologi; Naturvetenskap; Natural sciences;

    Abstract : Transition from a vegetative growth phase to flowering in plants occurs in response to both environmental conditions and endogenous signals. Identification of genes that are involved in regulating the time of flowering is of great importance in agri- and horticulture. READ MORE

  4. 2. Structural Transitions in Helical Peptides : The Influence of Water – Implications for Molecular Recognition and Protein Folding

    Author : Martin Lignell; Hans-Christian Becker; Kaare Teilum; Uppsala universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; protein dynamics; protein folding; molten globule; time-resolved fluorescence spectroscopy; CD spectroscopy; molecular recognition; structure-function paradigm; Chemical physics; Kemisk fysik; Physical Chemistry; Fysikalisk kemi;

    Abstract : Fluctuations in protein structure are vital to function. This contrasts the dominating structure-function paradigm, which connects the well-defined three-dimensional protein structure to its function. However, catalysis is observed in disordered enzymes, which lack a defined structure. READ MORE

  5. 3. Structural Information and Hidden Markov Models for Biological Sequence Analysis

    Author : Jeanette Tångrot; Bo Kågström; Uwe H. Sauer; Erik Sonnhammer; Umeå universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; HMM; structure alignment; protein structure; secondary structure; remote homologue; annotation; domain family; protein family; protein superfamily; protein fold recognition; Bioinformatics; Bioinformatik;

    Abstract : Bioinformatics is a fast-developing field, which makes use of computational methods to analyse and structure biological data. An important branch of bioinformatics is structure and function prediction of proteins, which is often based on finding relationships to already characterized proteins. READ MORE

  6. 4. Molecular recognition of proteins by functionalized folded polypeptide receptors

    Author : Theresa Andersson; Linköpings universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES;

    Abstract : This thesis describes the design, synthesis and characterization of synthetic receptor molecules for the recognition and binding of proteins with applications in bioseparation and biosensing. A 42-residue polypeptide, designed to fold into a helix-loop-helix motif and dimerize in solution to form a four-helix bundle, was used as the scaffold. READ MORE

  7. 5. Functional analysis of ligand recognition by the glucocorticoid receptor

    Author : Ulrika Lind; Karolinska Institutet; Karolinska Institutet; []
    Keywords : glucocorticoid receptor; steroid-binding; site-directed mutagenesis; protein-ligand interaction; mechanism of glucocorticoid action;

    Abstract : The glucocorticoid receptor (GR) is a ligand-inducible transcription factor that belongs to the superfamily of nuclear hormone receptors. It contains three structural and functional domains. READ MORE