Search for dissertations about: "follicular"

Showing result 21 - 25 of 126 swedish dissertations containing the word follicular.

  1. 21. Endocrine tumour development : With special focus on chromosome arms 1p and 11q

    University dissertation from Stockholm : Karolinska Institutet, Department of Molecular Medicine

    Author : Brita Nord; Karolinska Institutet.; Karolinska Institutet.; [2002]
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Endocrine tumour; Follicular thyroid tumour; Malignant melanoma; Midgut carcinoid; Pheochromocytoma; Abdominal paraganglioma; Merkel cell carcinoma; MEN1; SDHD; RIZ;

    Abstract : The overall goal of this thesis has been to characterise the involvement of chromosome arms 1p and 11 q in the development of endocrine tumours. The MEN1 gene was analysed as a candidate tumour suppressor gene by screening for mutations in follicular thyroid tumours, malignant melanomas, pheochromocytomas, and abdominal paragangliomas. READ MORE

  2. 22. Human ovarian follicles and oocytes : Collection, cryopreservation, culture and gene expression

    University dissertation from Stockholm : Karolinska Institutet, Department of Clinical Sciences

    Author : Pu Zhang; Karolinska Institutet.; Karolinska Institutet.; [2005]
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Ovarian follicle; oocyte; follicular aspirate; organ culture; cAMP; cGMP; cryopreservation; microarray; human gene expression; embryonic stem cell; preimplantation;

    Abstract : Infertility affects approximately 15% of couples globally. The most effective treatment today is in vitro fertilization. However, not all couples can be helped with the current techniques. To achieve better success, techniques of storage and in vitro maturation of ovarian follicles have to be improved. READ MORE

  3. 23. Behind the scenes of thyroid tumors : Underlying genetic mechanisms

    University dissertation from Stockholm : Karolinska Institutet, Department of Molecular Medicine and Surgery

    Author : Jia Jing Lee; Karolinska Institutet.; Karolinska Institutet.; [2007]
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Familial medullary thyroid cancer; follicular thyroid cancer; anaplastic thyroid cancer; CCND1; UBCH10; p16; RASSF1A; BRAF; array-CGH; tumor progression; global methylation; LINE-1; LUMA;

    Abstract : Thyroid cancer is the most frequently observed malignancy involving endocrine tissues. This group of diseases is also the major cause of death related to neoplasia of the endocrine system. Tumors in the thyroid gland are common in the general population and the majority represents benign follicular adenoma (FTA). READ MORE

  4. 24. Approaches for the localization and identification of human cancer genes

    University dissertation from Stockholm : Karolinska Institutet, Department of Molecular Medicine

    Author : Wong-Onn Lui; Karolinska Institutet.; Karolinska Institutet.; [2002]
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; CGH; FISH; SKY; karyotyping; SNP array; expression array; VHL-associated pheochromocytomas; hemangioblastomas; familial renal cell carcinoma; constitutional translocation; sporadic follicular thyroid tumors; chromosomal alterations; fusion oncogene; FTCF-PPAR gamma l; PAX8-PPAR gamma l.;

    Abstract : Chromosomal aberrations have been recognized as important observations that underpin the concept of a mutator phenotype in cancer. In this thesis, two basic strategies were applied to map the location of cancerrelated genes in several types of cancers. READ MORE

  5. 25. Chemotactic factors in the human follicle at ovulation

    University dissertation from Stockholm : Karolinska Institutet, Department of Molecular Medicine

    Author : Eva Runesson; Göteborgs universitet.; Gothenburg University.; [2000]
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; chemokine; follicle; gonadotropin; human; ovary; ovulation;

    Abstract : Ovulation is initiated by the midcycle gonadotropin surge, which leads to a controlled degradation of the follicle wall ending in follicular rupture and oocyte extrusion. The gonadotropins triggers several biochemical and biophysical changes such as vascular alterations, increased proteolytic enzyme activity and leukocyte extravasation, within the preovulatory follicle. READ MORE