Search for dissertations about: "follicular"

Showing result 6 - 10 of 146 swedish dissertations containing the word follicular.

  2. 6. Molecular mechanisms of ovarian follicular development and early embryogenesis

    Author : Nagaraju Gorre; Göteborgs universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; ovary; primordial follicles; Embryogenesis; PI3K-mTORC1 signaling;

    Abstract : In the mammalian ovary, the dormant primordial follicles are the source of developing follicles and fertilizable ova for the entire reproductive life. In addition, the duration of fertility of a female is determined by the initial size of her pool of primordial follicles and by the rate of its activation and depletion. READ MORE

  4. 7. THE ROLE OF DENDRITIC CELLS AND TYPE I INTERFERON IN THE GENERATION AND FUNCTION OF T FOLLICULAR HELPER CELLS

    Author : Helena Cucak; Immunologi; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; T follicular helper cells; Type I interferon; Dendritic cells;

    Abstract : Generation of long-lived plasma cells and memory B cells of high affinity takes place in germinal centers and depends on help from a specialized CD4+ T cell subset termed T follicular helper (Tfh) cells. These processes are crucial for long-term protection upon natural infection or in settings of vaccination, however they are also responsible for development of antibody-mediated autoimmune disease. READ MORE

  5. 8. Studies of phosphatidylinositol 3 kinase (PI3K) signaling pathway in mammalian ovarian follicle activation and development

    Author : Singareddy Rajareddy; Kui Liu; Anneli Stavreus-Evers; Umeå universitet; []
    Keywords : oocyte; follicular development; P13K pathway; medicinsk biokemi; Medical Biochemistry;

    Abstract : The intra-oocyte signaling pathways that control oocyte growth and early follicular development are largely unknown. The aim of this thesis was to investigate the regulation and functions of phosphatidylinositol 3 kinase (PI3K) pathway in the oocyte, focusing in the roles of Foxo3a, p27, and Pten (phosphatase and tensin homolog deleted on chromosome ten). READ MORE

  6. 9. Molecular Characterization of Diffuse Large B-cell Lymphoma and Aspects of Transformation

    Author : Mattias Berglund; Gunilla Enblad; Svetlana Lagercrantz; Christer Sundström; Catharina Larsson; Ingemar Ernberg; Uppsala universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Oncology; Diffuse large B-cell lymphoma; Hodgkin lymphoma; follicular lymphoma; transformation; comparative genomic hybridization; prognosis; Onkologi; Oncology; Onkologi;

    Abstract : Lymphomas are a heterogeneous group of neoplasias originating from B- or T-lymphocytes. In this thesis, we determined the genetic and immunophenotypic characterization of DLBCL and their prognostic impact. READ MORE

  7. 10. Genetic and molecular characterization of follicular thyroid tumors : diagnostic and prognostic aspects

    Author : Johan Paulsson; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : Follicular thyroid carcinoma (FTC) is the second most common thyroid malignancy and it sometimes metastasize to lungs and bone. A substantial subset of these tumors lacks an identified driver event and no well-established prognostic and diagnostic markers exist. READ MORE