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Showing result 1 - 5 of 18 swedish dissertations matching the above criteria.

  2. 1. Finding the unknowns in trans-translation

    Author : Natalia Ivanova; Måns Ehrenberg; Nenad Ban; Uppsala universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; Molecular biology; trans-translation; tmRNA; SmpB; kinetics; footprinting; Molekylärbiologi; Molecular biology; Molekylärbiologi;

    Abstract : Ribosomes stalled on problematic mRNAs can be rescued by a mechanism called trans-translation. This mechanism employs a dual transfer-messenger RNA molecule (tmRNA) together with a helper protein (SmpB). In this work we have used an in vitro translation system with pure components to further clarify the roles of tmRNA and SmpB in trans-translation. READ MORE

  4. 2. Transformations towards Sustainable Food Systems : Pathways, Governance, and Actors in a Swedish and European Union Context

    Author : Karin Eliasson; Tina-Simone Neset; Victoria Wibeck; Suvi Huttunen; Linköpings universitet; []
    Keywords : SAMHÄLLSVETENSKAP; SOCIAL SCIENCES; The European Green Deal; Food policy; Focus groups; Food systems; Biodiversity; Accountability; Agency; Phosphorus; Soybean; Footprinting; Den europeiska gröna given; Livsmedelspolitik; Fokusgrupper; Livsmedelssystem; Biodiversitet; Ansvarsskyldighet; Handlingsutrymme; Fosfor; Sojabönor; Fotavtryck;

    Abstract : Food systems are central to global sustainability, while being complex systems where places and people are intertwined over large distances and at different scales. Transformations towards sustainable food systems have been called for in both research and policy, and Sweden and the European Union have declared high ambitions to act as global leaders in these transformations. READ MORE

  5. 3. Computational and experimental approaches to regulatory genetic variation

    Author : Malin Andersen; Jacob Odeberg; John Peden; KTH; []
    Keywords : TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; Molecular biology; Genetics; single nucleotide polymprhism SNP ; regulatory SNP; transcription factor binding site; phylogenetic footprinting; allelic imbalance; EMSA; CD36; cardiovascular disease.; Genetic engineering including functional genomics; Genteknik inkl. funktionsgenomik;

    Abstract : Genetic variation is a strong risk factor for many human diseases, including diabetes, cancer, cardiovascular disease, depression, autoimmunity and asthma. Most of the disease genes identified so far alter the amino acid sequences of encoded proteins. READ MORE

  6. 4. The eukaryotic ribosome in focus : a chemical footprinting analysis of ribosome-ligand interactions in in vivo assembled complexes

    Author : Marika Salonen Sloma; Diarmaid Hughes; Stockholms universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; Cell biology; Cellbiologi; Zoological Cell Biology; zoologisk cellbiologi;

    Abstract : Protein synthesis is an essential biological process that occurs on ribosomes. The process requires an involvement of numerous components like mRNA, tRNA and translation factors. The mammalian 80S ribosome, the focus of this thesis, is composed of four rRNAs and approximately 80 proteins distributed in two subunits the 40S and 60S subunit. READ MORE

  7. 5. The eukaryotic ribosome : a chemical and enzymatic footprinting analysis of the structure and function of ribosomal RNA

    Author : Lovisa Holmberg; Stockholms universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES;

    Abstract : .... READ MORE