Search for dissertations about: "formalin test"

Showing result 1 - 5 of 12 swedish dissertations containing the words formalin test.

  2. 1. PACAP in adult sensory neurons - implications in injury and pain

    Author : Helen Jongsma Wallin; Institutionen för experimentell medicinsk vetenskap; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; peripheral nerve injury; PAC1; PACAP; neurotrophin; neuropeptide; inflammatory pain; inflammation; gracile nuclei; DRG; formalin test; neurofysiologi; neuropsykologi; Neurologi; neurophysiology; neuropsychology; Neurology; trk;

    Abstract : The data presented in this thesis deal with the neuropeptide pituitary adenylate cyclase-activating polypeptide (PACAP) in adult sensory neurons. We have used different injury and pain models to determine the involvement of PACAP during such conditions. The role of neurotrophins for PACAP expression was also investigated. READ MORE

  4. 2. Brain galanin sytems and their role in depression-like behaviour

    Author : Eugenia Kuteeva; Karolinska Institutet; Karolinska Institutet; []
    Keywords : 5-HT1A receptor; depression-like behaviour; forced swim test; galanin; galanin-overexpressing; galanin receptor; noradrenaline; serotonin; transgenic mouse;

    Abstract : The aim of the present thesis was to investigate the role of the neuropeptide galanin and galanin receptor subtypes in behavioural functions with a particular focus on depression-like behaviour. In agreement with its wide distribution in the central nervous system, galanin has been implicated in various functions, including regulation of reproduction, endocrine functions, antinociception, attention, learning and memory as well as regulation of mood. READ MORE

  5. 3. Evaluation of the Rift Valley fever vaccination program in Mozambican cattle

    Author : Belisário Moiane; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : Rift Valley fever (RVF) is a viral disease that is spread by various arthropods (primarily mosquitoes) and affects ruminants and humans. RVF has led to tremendous losses of livestock in many African countries, Saudi Arabia, and Yemen, and its zoonotic impact on human deaths has been documented in most of the endemic countries where large outbreaks have occurred. READ MORE

  6. 4. Synthesis and structure activity relationships of competitive NMDA antagonists with analgesic activity

    Author : Britt-Marie Swahn; Uppsala universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Pharmacy; FARMACI; PHARMACY; FARMACI; Organic Pharmaceutical Chemistry; organisk farmaceutisk kemi;

    Abstract : The compounds cis-3-(1-oxo-2-phosphonoethyl)-2-piperidinecarboxylic acid 1 and cis-3-(1-hydroxy-2-phosphonoethyl)-2-piperidinecarboxylic acid 2 were synthesized and found to be potent N-methyl-D-aspartate (NMDA) antagonists. NMR analysis showed that 1 prefers a 2eq,3ax chair conformation probably due to a conformer-stabilizing internal hydrogen bond. READ MORE

  7. 5. Human papillomaviruses in skin cancer and cervical cancer

    Author : Kristin Andersson; Malmö Klinisk mikrobiologi; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Human papillomavirus; serology co-factors; non-melanoma skin cancer;

    Abstract : The causal relationship between persistent genital infections with human papillomavirus (HPV) and development of cervical cancer is well established. In contrast, the significance of infections with cutaneous HPV for development of non-melanoma skin cancer (NMSC) is not well understood. READ MORE