Search for dissertations about: "freeze-substitution"

Found 4 swedish dissertations containing the word freeze-substitution.

2. 1. On amino acid neurotransmitters in the spinal cord motor nuclei

   Author : Göran Örnung; Karolinska Institutet; Karolinska Institutet; []
   Keywords : neurotransmitter; aspartate; glutamate; GABA. glycine; homocysteate; taurine; ultrastructure; freeze-substitution; immunocytochemistry; bouton; synaptic input; motoneuron; strech reflex; spinal cord; cat. rat;

   Abstract : Using pre- and post-embedding immunocytochemistry, the distribution of six amino acid neurotransmitter candidates, with special reference to y-amino-butyric acid (GABA), glycine and glutamate was examined in boutons apposing somata and dendrites in the lumbar motor nuclei of the cat spinal cord. The monosynaptic connection between muscle spindle I a afferents and motoneurons regarding content of neuroactive amino acid and complement of amino acid receptors in the postsynaptic membrane was studied in the rat. READ MORE

4. 2. The central cervical nucleus in the rat : studies on connectivity, function and chemical transmission

   Author : Birger Ragnarson; Karolinska Institutet; Karolinska Institutet; []
   Keywords : Amino acid transmitter AMPA Anterograde Cerebellum Cervical Choleragenoid Electron microscopy Freeze-substitution Glutamate Horseradish peroxidase Ia primary afferent Immunogold Immunocytochemistry Locomotion Motoneuron NMDA Neck muscle Postembedding;

   Abstract : The central cervical nucleus (CCN) is a spinocerebellar cell group in the upper cervical spinal cord (rat: Cl-C3), that is known to receive a powerful primary afferent input from, the upper cervical spinal nerves (C 1-C4), originating mainly from muscle spindle afferents in deep dorsal neck muscles and from the ipsi- and contralateral vestibular nuclei. It projects to the cerebellar vermis bilaterally and to all the vestibular nuclei contralaterally. READ MORE

5. 3. The role of multifunctional scaffolding proteins in the synaptic vesicle cycle

   Author : Wei Jiao; Karolinska Institutet; Karolinska Institutet; []
   Keywords : ;

   Abstract : Fast synaptic transmission occurs at specialized junctions between neurons referred to as chemical synapses. Action potentials induce an influx of calcium ions into presynaptic terminals, which contain neurotransmitter-filled synaptic vesicles (SVs), triggering fusion of the vesicles with the plasma membrane and resulting in the release of neurotransmitters. READ MORE

6. 4. Molecular organization and in situ assembly of the human skin barrier

   Author : Lianne den Hollander; Karolinska Institutet; Karolinska Institutet; []
   Keywords : ;

   Abstract : A deficient skin barrier function is a characteristic feature of skin diseases such as eczema, psoriasis and the ichtyoses. A malformation of the lipid matrix might be a major factor in barrier deficient skin disease. READ MORE