Search for dissertations about: "frontotemporal lobar degeneration"

Showing result 1 - 5 of 8 swedish dissertations containing the words frontotemporal lobar degeneration.

  1. 1. Molecular Mechanisms of Frontotemporal Lobar Degeneration

    Author : Lena Skoglund; Anna Glaser; Martin Ingelsson; Lars Lannfelt; Stuart Pickering-Brown; Uppsala universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Frontotemporal lobar degeneration; Frontotemporal dementia; Tau; Progranulin; Alternative splicing; Nonsense-mediated decay; Haploinsufficiency;

    Abstract : The aim of this thesis was to identify genetic factors involved in frontotemporal lobar degeneration (FTLD), a neurodegenerative disorder clinically characterised by a progressive change in personality, behaviour and language. FTLD is a genetically complex disorder and a positive family history is found in up to 40% of the cases. READ MORE

  2. 2. Frontotemporal dementia - symptoms and brain pathology

    Author : Maria Landqvist; Lund Psykiatri; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; genetics; neuropsychiatric symptoms; protein pathology; clinical diagnosis; neuropathology; biomarkers; Frontotemporal dementia;

    Abstract : Frontotemporal dementia (FTD) is the clinical term for a heterogeneous group of dementia disorders with symptoms emerging from frontotemporal lobar degeneration (FTLD). FTD encompasses the behavioural variant (bvFTD) and the progressive aphasias: progressive non-fluent aphasia (PNFA) and semantic dementia (SD). READ MORE

  3. 3. Neuropathological findings and staging in dementia

    Author : Hans Brunnström; Tumörmikromiljö; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Alzheimer disease; concordance; dementia; diagnostics; frontotemporal lobar degeneration; grading; Lewy body disease; locus coeruleus; neuropathology; prevalence; staging; vascular dementia;

    Abstract : Dementia is a clinical syndrome with the development of impairment in multiple cognitive functions (including memory), severe enough to interfere with activities of daily living, as the main symptom. There are a large number of disorders that can lead to dementia, and neuropathological examination after death is necessary to determine the underlying cause with certainty. READ MORE

  4. 4. Microvascular brain raspberries: A clinicopathological study

    Author : Henric Ek-Olofsson; Lund Patologi; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; cerebrovascular disease; cerebral small vessel disease; vascular dementia; neurodegenerative disease; frontotemporal lobar degeneration; hypertension;

    Abstract : .... READ MORE

  5. 5. On characterisation and diagnosis of frontotemporal lobar degeneration syndromes : with special reference to the progressive aphasias

    Author : N Christian Andersen; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : Alzheimer's disease (AD) is the most common dementing brain disease, with episodic memory impairment as a characteristic early feature. However, not all primary degenerative brain syndromes include prominent deficits in day-to-day memorizing. READ MORE