Search for dissertations about: "gabapentin thesis"
Showing result 6 - 9 of 9 swedish dissertations containing the words gabapentin thesis.
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6. Development of Substance P 1–7 Related Peptides and Peptidomimetics : Targeting Neuropathic Pain
Abstract : The neuropeptide substance P 1–7 (SP1–7, H-Arg1-Pro2-Lys3-Pro4-Gln5-Gln6-Phe7-OH) and its amidated analogue SP1–7 amide, have displayed intriguing effects in experimental models for neuropathic pain acting on a specific, yet unknown SP1–7 target. The aim of this thesis was to design and synthesise SP1–7 related peptides and peptidomimetics, to be used as research tools to study the SP1–7 system, and to serve as drug leads in the neuropathic pain area. READ MORE
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7. Role of spinal and peripheral HMGB1 in arthritis-induced pain
Abstract : Chronic pain is one of the most debilitating and repeatedly reported symptoms by rheumatoid arthritis (RA) patients. Despite good disease control achieved with disease modifying antirheumatic drugs (DMARDs), joint pain remains a major problem for a subgroup of patients. READ MORE
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8. Antibody- and osteoclast-dependent mechanisms of chronic pain
Abstract : Chronic pain is a frequent condition that affects approximately 20% of worldwide population with a higher prevalence among women. Due to the lack of optimal treatment, chronic pain leads to decreased life quality as well as significant physical and psychological complications. READ MORE
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9. Newer antiepileptic drugs in women of child-bearing age : pharmacokinetic studies during pregnancy, breastfeeding, and contraception
Abstract : Epilepsy is a common neurological disorder, affecting men and women almost equally. It has been estimated that 0.3 to 0.4% of pregnant women have epilepsy. READ MORE