Search for dissertations about: "galectin 8 thesis"
Showing result 1 - 5 of 23 swedish dissertations containing the words galectin 8 thesis.
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1. Galectin binding proteins in serum and bronchoalveolar lavage -in healthy and pathological conditions
Abstract : Galectins are carbohydrate binding proteins, implicated in conditions of both inflammation and cancer. Connections between chronic inflammation and cancer are proposed by the increased remodelling and proliferation that occurs, leading to enhanced survival and proliferation of malignant cells. READ MORE
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2. Novel glycomimetic inhibitors and proteolysis-targeting chimeras for human galectins
Abstract : Galectins are a family of soluble proteins that bind β-D-galactopyranoside-containing glycoconjugates through their conserved carbohydrate-recognition domains. Galectins have emerged as promising drug targets due to their involvement in various pathological conditions, such as tumor growth and metastasis, autoimmune and inflammatory diseases, as well as metabolic disorders. READ MORE
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3. Effects of galectins and antibodies in HIV infection; Novel Assays
Abstract : The high variability of the HIV envelope glycoproteins (Env), and their heavy glycan coating, contributes to the limited host immune control. Still, broadly neutralizing antibodies (bnAbs) are found in some chronically infected HIV-infected individuals, which has spurred the research on antibody-based vaccines. READ MORE
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4. Galectin-3 Ligand Binding: Mechanism and Driving Forces
Abstract : .... READ MORE
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5. FROM SERUM TO TISSUE: GALECTIN-BINDING GLYCOFORMS OF SERUM GLYCOPROTEINS AS FUNCTIONAL BIOMARKERS
Abstract : Galectins are small soluble proteins defined by a conserved sequence motif that forms a defining β-galactoside binding site shared among galectins; adjacent binding sites give each galectin a unique fine specificity for a specific subset of galactose containing glycans. A wealth of data now suggests important roles of galectins in both cancer and inflammation. READ MORE