Search for dissertations about: "ganglioside-lactam"

Found 1 swedish dissertation containing the word ganglioside-lactam.

2. 1. Synthesis of Conformationally Restricted Oligosaccharides

   Author : Michael Wilstermann; Centrum för analys och syntes; []
   Keywords : NATURVETENSKAP; NATURAL SCIENCES; Streptococcus suis; E. coli; neoglycolipid; ganglioside-lactam; xylose; methylene acetal; sialic acid; Conformational Restriction; galabiose; Organic chemistry; Organisk kemi;

   Abstract : Gangliosides are sialic acid-containing glycosphingolipids that often are present in increased amounts on tumor cells. Since the gangliosides are hydroxy-acids, they can form lactones. The lactones have been suspected to be more immunogenic than the open forms, but are in practise poor immunogens due to their ease of hydrolysis. READ MORE