Search for dissertations about: "gastrointestinal cell lines"

Showing result 1 - 5 of 11 swedish dissertations containing the words gastrointestinal cell lines.

  1. 1. Mucus and mucins during gastrointestinal infections

    Author : Nazanin Navabi; Göteborgs universitet; Göteborgs universitet; Gothenburg University; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; mucin; gastrointestinal cell lines; mucus layer; secreted mucin; cell surface mucin; H. pylori; C. rodentium; ETEC; mucin secretion; goblet cells;

    Abstract : The gastrointestinal tract is protected by a continuously secreted mucus layer formed by mucin glycoproteins. The mucus layer and mucins change dynamically during infection. The main focus of this thesis was to investigate the changes in mucin and the mucus layer in the gastrointestinal tract during infection with the gastrointestinal pathogens C. READ MORE

  2. 2. Gene Expression in mESC Deficient in FGFR Signalling and the Identification of the Novel Gene Ened

    Author : Renata Gustafsson; Muskelbiologi; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; embryonic stem cells; differentiation; FGF FGFR signalling; gene expression; microarray; Ened; early embryonic development;

    Abstract : Embryonic stem cells (ESCs) are derived from the inner cell mass (ICM) of blastocyst stage embryos, and upon differentiation into embryoid bodies (EBs) they recapitulate the genetic, cellular and morphological events occurring in early embryogenesis. Among several signalling pathways and inductive factors, the fibroblast growth factors (FGFs) and their receptors (FGFRs) have been shown to be important during early embryogenesis. READ MORE

  3. 3. Role of oxidative stress response in radiosensitivity

    Author : Ali Pour Khavari; Siamak Haghdoost; Bo Stenerlöw; Stockholms universitet; []
    Keywords : NATURAL SCIENCES; NATURVETENSKAP; NATURVETENSKAP; NATURAL SCIENCES; Oxidative stress; radiosensitivity; 8-oxo-dG; DNA-repair; NRF2; glioblastoma; radiotherapy; molekylär biovetenskap; Molecular Bioscience;

    Abstract : The quality of the ionizing radiation (IR) can be described in terms of its nature, photons or particles, and their corresponding energies. The energy is classified in terms of High or Low linear energy transfer that will produce a different distribution of DNA damage and other molecules in the cell either by direct action or indirect action. READ MORE

  4. 4. MicroRNA and energy metabolism in gastrointestinal tumors

    Author : Wen-Kuan Huang; Karolinska Institutet; Karolinska Institutet; []
    Keywords : MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP;

    Abstract : MicroRNAs (miRNAs) contribute to cancer development and drug resistance via cellular biological processes, including metabolic pathways. Energy metabolism plays a significant role to maintain tumor proliferation in gastrointestinal (GI) cancers. However, the roles of miRNAs and energy metabolism in GI cancers are not fully understood. READ MORE

  5. 5. Novel aspects of the molecular biology of gastrointestinal stromal tumors

    Author : Erik Berglund; Karolinska Institutet; Karolinska Institutet; []
    Keywords : MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP;

    Abstract : The gastrointestinal stromal tumor (GIST) is the most common mesenchymal tumor in the gastrointestinal tract (GI). Historically, these tumors were commonly mistaken for myogenic and neurogenic masses, and then eventually came to be recognized as a distinct type of soft-tissue sarcoma through ultrastructural findings and specific immunomarkers. READ MORE