Search for dissertations about: "gastrointestinal cell lines"

Showing result 1 - 5 of 13 swedish dissertations containing the words gastrointestinal cell lines.

2. 1. Mucus and mucins during gastrointestinal infections

   Author : Nazanin Navabi; Göteborgs universitet; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; mucin; gastrointestinal cell lines; mucus layer; secreted mucin; cell surface mucin; H. pylori; C. rodentium; ETEC; mucin secretion; goblet cells;

   Abstract : The gastrointestinal tract is protected by a continuously secreted mucus layer formed by mucin glycoproteins. The mucus layer and mucins change dynamically during infection. The main focus of this thesis was to investigate the changes in mucin and the mucus layer in the gastrointestinal tract during infection with the gastrointestinal pathogens C. READ MORE

4. 2. Functions of PDGF-A and -C. Essential ligands for the PDGF alpha receptor

   Author : Hans Boström; Göteborgs universitet; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; platelet-derived growth factor; PDGF-A; PDGF-C; PDGF alpha receptor; extracellular retention; gene targeting; mouse development; epithelial-mesenchymal interaction; lung; alveolar formation; spina bifida; gastrointestinal villus;

   Abstract : Altered protein kinase activity is a contributing factor in many diseases including most formsof human malignancies, and there is reason to believe that protein kinases will prove to be majordrug targets in the treatment of cancer. Protein kinases mediate most of the signal transduction ineukaryotic cells, regulating cellular events such as transcription, metabolism, proliferation,cytoskeletal rearrangement, migration, differentiation and apoptosis. READ MORE

5. 3. Gene Expression in mESC Deficient in FGFR Signalling and the Identification of the Novel Gene Ened

   Author : Renata Gustafsson; Muskelbiologi; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; embryonic stem cells; differentiation; FGF FGFR signalling; gene expression; microarray; Ened; early embryonic development;

   Abstract : Embryonic stem cells (ESCs) are derived from the inner cell mass (ICM) of blastocyst stage embryos, and upon differentiation into embryoid bodies (EBs) they recapitulate the genetic, cellular and morphological events occurring in early embryogenesis. Among several signalling pathways and inductive factors, the fibroblast growth factors (FGFs) and their receptors (FGFRs) have been shown to be important during early embryogenesis. READ MORE

6. 4. Role of oxidative stress response in radiosensitivity

   Author : Ali Pour Khavari; Siamak Haghdoost; Bo Stenerlöw; Stockholms universitet; []
   Keywords : NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; Oxidative stress; radiosensitivity; 8-oxo-dG; DNA-repair; NRF2; glioblastoma; radiotherapy; molekylär biovetenskap; Molecular Bioscience;

   Abstract : The quality of the ionizing radiation (IR) can be described in terms of its nature, photons or particles, and their corresponding energies. The energy is classified in terms of High or Low linear energy transfer that will produce a different distribution of DNA damage and other molecules in the cell either by direct action or indirect action. READ MORE

7. 5. MicroRNA and energy metabolism in gastrointestinal tumors

   Author : Wen-Kuan Huang; Karolinska Institutet; Karolinska Institutet; []
   Keywords : ;

   Abstract : MicroRNAs (miRNAs) contribute to cancer development and drug resistance via cellular biological processes, including metabolic pathways. Energy metabolism plays a significant role to maintain tumor proliferation in gastrointestinal (GI) cancers. However, the roles of miRNAs and energy metabolism in GI cancers are not fully understood. READ MORE