Advanced search

Showing result 1 - 5 of 69 swedish dissertations matching the above criteria.

2. 1. On gastrointestinal viral infections

   Author : Thomas Beck-Friis; Göteborgs universitet; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; norovirus; rotavirus; SARS-CoV-2; gastroenteritis; diagnosis; elderly; epidemiology; humidity; COVID-19; genomic structural variation;

   Abstract : Gastrointestinal viral infections cause considerable morbidity and mortality worldwide. Many factors influencing clinical presentation, disease severity, epidemiology, and transmission are not fully understood. READ MORE

4. 2. Mucus and mucins during gastrointestinal infections

   Author : Nazanin Navabi; Göteborgs universitet; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; mucin; gastrointestinal cell lines; mucus layer; secreted mucin; cell surface mucin; H. pylori; C. rodentium; ETEC; mucin secretion; goblet cells;

   Abstract : The gastrointestinal tract is protected by a continuously secreted mucus layer formed by mucin glycoproteins. The mucus layer and mucins change dynamically during infection. The main focus of this thesis was to investigate the changes in mucin and the mucus layer in the gastrointestinal tract during infection with the gastrointestinal pathogens C. READ MORE

5. 3. Physical and psychological characteristics in adolescence and risk of gastrointestinal disease in adulthood

   Author : Carren Anyango Melinder; Scott Montgomery; Ayako Hiyoshi; Katja Fall; Seeromanie Harding; Örebro universitet; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Physical fitness; stress resilience; adolescence; inflammatory bowel disease; peptic ulcer disease; gastrointestinal infections;

   Abstract : Background and objectives: Physical fitness and stress resilience may influence the risk of gastrointestinal (GI) disease. High physical fitness level may reduce levels of systemic inflammation while psychosocial stress exposure can increase inflammation levels and intestinal permeability. READ MORE

6. 4. Gastrointestinal norovirus infections and the development of the next generation of mucosal vaccines

   Author : Inga Rimkute; Göteborgs universitet; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; human norovirus; gastrointestinal infection; mucosal vaccine; subcomponent vaccine; human intestinal enteroids; histo-blood group antigens; lipidomics; glycoproteomics; glycosphingolipids;

   Abstract : Human norovirus (HuNoV) is the causative agent of the winter vomiting disease and the leading cause of outbreaks of gastrointestinal infections across all settings and age groups in the world. The virus is highly contagious making outbreaks difficult or often impossible to control and having a high impact on societal costs and resources. READ MORE

7. 5. Passive immunisation as therapy for gastrointestinal infections in children

   Author : Thomas Casswall; Karolinska Institutet; Karolinska Institutet; []
   Keywords : Passive immunisation; treatment; bovine antibodies; chicken antibodies; rotavirus; Escherichia coli; ETEC; EPEC; Helicobacter pylori; clinical trials; infants; children;

   Abstract : Several prophylactic studies in animals and humans have shown potential efficacy of oral therapy with non-human antibodies against different pathogens. Passive immunisation with oral antibodies against different pathogens is an attractive way to treat different gastrointestinal infections caused by pathogens such as rotavirus or enteropathogenic and enterotoxigenic Escherichia coli (EPEC; ETEC). READ MORE