Search for dissertations about: "gene expression analysis DNA array"
Showing result 1 - 5 of 45 swedish dissertations containing the words gene expression analysis DNA array.
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1. Statistical analysis of gene expression data
Abstract : Microarray technology has become one of the most important tools for genome-wide mRNA measurements. The technique has been successfully applied to many areas in modern biology including cancer research, identification of drug targets, and categorization of genes involved in the cell cycle. READ MORE
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2. Gene Expression and DNA Methylation in Acute Lymphoblastic Leukemia
Abstract : Pediatric acute lymphoblastic leukemia (ALL) is the most common malignancy in children, which results from the malignant transformation of progenitor cells in the bone marrow into leukemic cells. The precise mechanisms for this transformation are not well defined, however recent studies suggest that aberrant regulation of gene expression or DNA methylation may play an important role. READ MORE
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3. Weighted Analysis of Microarray Experiments
Abstract : DNA microarrays are strikingly efficient tools for analysing gene expression for large sets of genes simultaneously. The aim is often to identify genes which are differentially expressed between some studied conditions, thereby gaining insight into which cellular mechanisms are differently active between the conditions. READ MORE
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4. Genomic profiling of breast cancer by microarray-based technology and bioinformatics
Abstract : Cancer is a genetic disease that arises when a cell acquires unlimited growth potential through a series of mutational events, which target genes essential for normal cell control and maintenance. Breast cancer is one of the most frequent malignancies in women worldwide, and it is characterized by heterogeneous tumor biology, histological subtypes, variable prognosis and variable responsiveness to treatment. READ MORE
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5. Epigenetic dysregulation in relation to psychiatric traits in adolescence and adulthood
Abstract : Epigenetics has evolved into a key research focus in the field of psychiatry. DNA methylation is the most researched epigenetic mechanism. In paper I-III, 130 and 93 adolescents were randomly recruited at two separate intervals. READ MORE