Search for dissertations about: "gene expression data"

Showing result 21 - 25 of 1025 swedish dissertations containing the words gene expression data.

  2. 21. Coordination of gene expression programs

    Author : Julie Lorent; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : Most cellular processes depend on the activity and interactions of proteins. The proteome, i.e. the entire set of proteins in a specific condition, is shaped by regulation of transcription, mRNA-degradation, -processing, -storage, -translation and protein degradation. READ MORE

  4. 22. Spatially Resolved Gene Expression Analysis

    Author : Michaela Asp; Joakim Lundeberg; Patrik Ståhl; Thierry Voet; KTH; []
    Keywords : RNA; RNA-sequencing; transcriptomics; spatial transcriptomics; single cells; Bioteknologi; Biotechnology;

    Abstract : Spatially resolved transcriptomics has greatly expanded our knowledge of complex multicellular biological systems. To date, several technologies have been developed that combine gene expression data with information about its spatial tissue context. READ MORE

  5. 23. Exploring the Boundaries of Gene Regulatory Network Inference

    Author : Andreas Tjärnberg; Erik Sonnhammer; Richard Bonneau; Stockholms universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; GRN; gene regulatory network; network inference; signal to noise ratio; model selection; variable selection; data properties; reverse engineering; ordinary differential equations; gene networks; linear regression; lasso; Biochemistry towards Bioinformatics; biokemi med inriktning mot bioinformatik;

    Abstract : To understand how the components of a complex system like the biological cell interact and regulate each other, we need to collect data for how the components respond to system perturbations. Such data can then be used to solve the inverse problem of inferring a network that describes how the pieces influence each other. READ MORE

  6. 24. Approaches to differential gene expression analysis in atherosclerosis

    Author : Tove Andersson; KTH; []
    Keywords : representational difference analysis; gene expression profiling; microarray analysis; atherosclerosis; foam cell formation;

    Abstract : Today’s rapid development of powerful tools for geneexpression analysis provides unprecedented resources forelucidating complex molecular events.The objective of this workhas been to apply, combine andevaluate tools for analysis of differential gene expressionusing atherosclerosis as a model system. READ MORE

  7. 25. Regulation of human macrophage gene expression by oxidized low density lipoprotein. Studies on tumor necrosis factor-a and global gene expression profiles

    Author : Mikael C. O. Englund; Göteborgs universitet; []
    Keywords : atherosclerosis; macrophage; gene expression; TNF-a; oxidized LDL; oxysterol; transcription factor; microarray;

    Abstract : Atherosclerosis is a multifactorial and progressive disease that is characterized by a focal thickening of the arteries caused by accumulation of lipoproteins, extracellular matrix, and the migration and proliferation of various cell types. Among the cells found in atherosclerotic lesions are macrophages, which accumulate lipids and are transformed into foam cells. READ MORE