Search for dissertations about: "gene frequency"

Showing result 1 - 5 of 383 swedish dissertations containing the words gene frequency.

2. 1. Retroviral gene transfer to repopulating hematopoietic cells

   Author : Thomas Relander; Tumörmikromiljö; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; GLVR-1; VSV-G; amphotropic; GALV; long-term bone marrow culture; NOD SCID; retroviral vector; hematopoietic stem cells; stem cells; gene transfer; gene therapy; fibronectin; Clinical genetics; Klinisk genetik;

   Abstract : Hematopoietic stem cells (HSCs) have the capacity to maintain hematopoiesis throughout life. HSCs are ideal targets for permanent gene transfer, as the transgene will be expressed in all the progeny of the gene-modified stem cells. READ MORE

4. 2. Hypospadias : gene mapping and candidate gene studied

   Author : Thi Thai Hanh Trinh; Karolinska Institutet; Karolinska Institutet; []
   Keywords : ;

   Abstract : Hypospadias is a common congenital malformation in boys, characterized by incomplete fusion of the urethral folds, abnormal opening of urethra and different degrees of curvature of the penis. In Sweden, the incidence of hypospadias is 1.14 per 300 male live-births according to the annual Swedish Malformation Registry. READ MORE

5. 3. Bayesian Modeling of Directional Data with Acoustic and Other Applications

   Author : Jalil Taghia; Arne Leijon; W. Bastiaan Kleijn; KTH; []
   Keywords : TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; Directional statistics; directional distributions; axial distributions; von Mises-Fisher distribution; complex Watson distribution; complex Bingham distribution; Bayesian inference; probabilistic modeling; variational inference; two-dimensional hidden Markov models; Markov chain; blind source separation; frequency domain BSS; underdetermined BSS; online BSS; Bayesian recursive; gene expression data; gene-microarray data; line spectral frequency; speaker identification. ii;

   Abstract : A direction is defined here as a multi-dimensional unit vector. Such unitvectors form directional data. Closely related to directional data are axialdata for which each direction is equivalent to the opposite direction.Directional data and axial data arise in various fields of science. READ MORE

6. 4. Gene conversion of the mouse MHC class II

   Author : Kari Högstrand; Ulf Gyllensten; Stockholms universitet; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MHC; H2; gene conversion; evolution; polymorphism; Immunology; Immunologi; immunologi; Immunology;

   Abstract : The major histocompatibility complex (MHC) is the most polymorphic vertebrate gene loci known to exist. Gene products of the MHC are responsible for presentation of antigen derived peptides to T cells of the immune system, which thereby become activated and involved in the elimination of particles recognised as non-self. READ MORE

7. 5. Gene therapy for epilepsy: resculpturing synaptic transmission with neuropeptides

   Author : Andreas Toft Sörensen; Experimentell Epilepsi; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; LTP; synaptic plasticity; synaptic transmission; electrophysiology; Y5 receptor; Y2 receptor; neuropeptide Y NPY ; hippocampus; gene therapy; epilepsy; memory; activity-dependent release; volume transmission;

   Abstract : Intractable seizures and lack of effective antiepileptic drugs (AED) are severe and common conditions affecting many patients with epilepsy. Thus, there is an urgent need to develop new therapies in epilepsy. The search for novel treatments has identified several neuropeptide systems as potential targets for future therapeutic interventions. READ MORE