Search for dissertations about: "gene network analysis"
Showing result 1 - 5 of 134 swedish dissertations containing the words gene network analysis.
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1. Network and gene expression analyses for understanding protein function
Abstract : Biological function is the result of a complex network of functional associations between genes or their products. Modeling the dynamics underlying biological networks is one of the big challenges in bioinformatics. READ MORE
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2. Functional association networks for disease gene prediction
Abstract : Mapping of the human genome has been instrumental in understanding diseasescaused by changes in single genes. However, disease mechanisms involvingmultiple genes have proven to be much more elusive. Their complexityemerges from interactions of intracellular molecules and makes them immuneto the traditional reductionist approach. READ MORE
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3. Exploring the Boundaries of Gene Regulatory Network Inference
Abstract : To understand how the components of a complex system like the biological cell interact and regulate each other, we need to collect data for how the components respond to system perturbations. Such data can then be used to solve the inverse problem of inferring a network that describes how the pieces influence each other. READ MORE
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4. Global functional association network inference and crosstalk analysis for pathway annotation
Abstract : Cell functions are steered by complex interactions of gene products, like forming a temporary or stable complex, altering gene expression or catalyzing a reaction. Mapping these interactions is the key in understanding biological processes and therefore is the focus of numerous experiments and studies. READ MORE
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5. Computational analysis on the effects of variations in T and B cells. Primary immunodeficiencies and cancer neoepitopes
Abstract : Computational approaches are essential to study the effects of inborn and somatic variations. Results from such studies contribute to better diagnosis and therapies. Primary immunodeficiencies (PIDs) are rare inborn defects of key immune response genes. Somatic variations are main drivers of most cancers. READ MORE