Search for dissertations about: "gene network analysis"
Showing result 11 - 15 of 134 swedish dissertations containing the words gene network analysis.
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11. Omics Data Analysis of Complex Diseases and Traits
Abstract : Following the advent of the high-throughput techniques for producing massive omics data, new possibilities and challenges have also emerged in different fields of biology and medicine. Dealing with such data on different scales with different scopes such as genomics, transcriptomics, proteomics and metabolomics, demands appropriate data collection, preprocessing, statistical analysis, interpretation and visualization. READ MORE
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12. Integrative Analysis of Dynamic Networks
Abstract : Networks play a central role in several disciplines such as computational biology, social network analysis, transportationplanning and many others; and consequently, several methods have been developed for network analysis. However, in many cases, the study of a single network is insufficient to discover patterns with multiple facets and subtlesignals. READ MORE
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13. Big data networks and orthology analysis
Abstract : Understanding biological systems in complex organisms is important in life science in order to comprehend the interplay of genes, proteins, and compounds causing complex diseases. As biological systems are intricate, bioinformatics tools, models, and algorithms are of the utmost importance to understand the bigger picture and decipher biological meaning from the vast amounts of information available from biological experiments and predictions. READ MORE
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14. Using Trees to Capture Reticulate Evolution : Lateral Gene Transfers and Cancer Progression
Abstract : The historic relationship of species and genes are traditionally depicted using trees. However, not all evolutionary histories are adequately captured by bifurcating processes and an increasing amount of research is devoted towards using networks or network-like structures to capture evolutionary history. READ MORE
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15. Systematic Modular Approaches to Reveal DNA Damage Responses in Mammalian Cells
Abstract : Cancer therapy operates by inflicting damage in malignant cells. The most lethal target is the genomic DNA. As a single double strand DNA break has the potential to kill the cell, mechanisms have evolved to detect and block propagation of the damage. READ MORE