Search for dissertations about: "gene network analysis"

Showing result 6 - 10 of 134 swedish dissertations containing the words gene network analysis.

2. 6. Systems Biology of Type 2 Diabetes in Skeletal Muscle

   Author : Leif Väremo; Chalmers tekniska högskola; []
   Keywords : NATURVETENSKAP; NATURAL SCIENCES; genome-scale metabolic model; metabolism; skeletal muscle; myocyte; type 2 diabetes; network analysis; gene-set analysis; transcriptomics; gene expression; obesity;

   Abstract : Type 2 diabetes (T2D) is a heterogeneous and complex disease that currently affects more than 350 million people worldwide. A wide range of risk factors influence the pathogenesis of T2D, including genetic and epigenetic components, as well as controllable factors such as diet, obesity, and sedentary lifestyle. READ MORE

4. 7. Gene networks from high-throughput data : Reverse engineering and analysis

   Author : Mika Gustafsson; Michael Hörnquist; Jesper Tegnér; Reinhard Guthke; Linköpings universitet; []
   Keywords : NATURAL SCIENCES; NATURVETENSKAP;

   Abstract : Experimental innovations starting in the 1990’s leading to the advent of high-throughput experiments in cellular biology have made it possible to measure thousands of genes simultaneously at a modest cost. This enables the discovery of new unexpected relationships between genes in addition to the possibility of falsify existing. READ MORE

5. 8. Metabolic analysis of shikimic acid producing Escherichia coli

   Author : Louise Johansson; Avdelningen för kemiteknik; []
   Keywords : TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; Kemiteknik och kemisk teknologi; Biokemi; metabolism; Chemical technology and engineering; transcriptome analysis; phosphorus-limitation; carbon-limitation; fed-batch; chemostat; batch; fermentation technology; Escherichia coli; shikimic acid; Biotechnology; Bioteknik; Metabolism; Biochemistry; principal component analysis; 2D-fluorescence spectrophotometry; metabolic flux analysis; carbon-rich;

   Abstract : Shikimic acid production using recombinant E.coli has been developed during the past 15 years due to the increased demand of this product, primarily as a starting material for the anti-influensa medicine Tamiflu?. A detailed metabolic analysis of a shikimic acid producing E. READ MORE

6. 9. A genomic approach to smooth muscle differentiation and diversity

   Author : Sven Nelander; Göteborgs universitet; []
   Keywords : Keywords: smooth muscle; phenotype; transcriptional regulation; differentiation; transcriptome; microarray; computational prediction; co-expression network; regulatory sequence analysis; gene module; gene battery;

   Abstract : Smooth muscle cells (SMCs) are a broad class of contractile cells that are found in a number of organs systems, including the vasculature, the urogenital system, the bronchi and the gastrointestinal tract. The two main functions exerted by SMCs are to provide contractile force and to synthesize structural components of the extracellular matrix. READ MORE

7. 10. Gene Regulatory Networks: Dynamics and Stability

   Author : Carl Troein; Beräkningsbiologi och biologisk fysik - Genomgår omorganisation; []
   Keywords : NATURVETENSKAP; NATURAL SCIENCES; systems; control; Datalogi; numerisk analys; system; kontroll; Computer science; numerical analysis; Fysik; biomathematics biometrics; Bioinformatik; medicinsk informatik; biomatematik; Physics; medical informatics; transcriptional regulation; gene regulatory networks; Bioinformatics; signaling pathway profiling; stem cell regulation; metabolic pathway; fitness; nested canalyzing rules; Kauffman networks; random Boolean networks; Fysicumarkivet:2007:Troein;

   Abstract : Life as we know it is based on cells that use proteins and RNA to carry out metabolism, self-replication, and other essential tasks. The genes that code for these molecules are encoded in DNA, and through the processes of transcription and translation the cell expresses its genes. READ MORE