Search for dissertations about: "genes and the heart"

Showing result 1 - 5 of 131 swedish dissertations containing the words genes and the heart.

  1. 1. The Physiology of Chicken Domestication : Involvement of the HPA-axis and the Autonomic Nervous System

    Author : Magnus Elfwing; Jordi Altimiras; Michael Axelsson; Linköpings universitet; []
    Keywords : NATURAL SCIENCES; NATURVETENSKAP; NATURVETENSKAP; NATURAL SCIENCES; Domestication; chickens; HPA-axis; autonomic nervous system; heart rate; allometry;

    Abstract : Domesticering är en urvalsprocess för önskvärda egenskaper hos djur som över tid förändrar deras utseende, beteende och genetik. Några exempel av djur som genomgått denna riktade avel är vargen, mufflon, uroxen, vildsvinet och den röda djungelhönan som vi idag känner som hunden, fåret, kon, grisen och slaktkycklingen. READ MORE

  2. 2. Systemic lupus erythematosus and rheumatoid arthritis : analyses of candidate genes involved in immune functions, for susceptibility and severity

    Author : Martin Johansson; Solbritt Rantapää Dahlqvist; Ingrid Lundberg; Umeå universitet; []
    Keywords : MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; SLE; RA; oestrogen; renal disorder; ESR1; PDCD1; PTPN22; association; severity; Rheumatology; Reumatologi; Medicine; medicin;

    Abstract : Systemic lupus erythematosus (SLE) is an autoimmune rheumatic disease with systemic manifestations characterized by auto-antibodies directed against different parts of the cell nucleus including DNA, histones and ribosomes. The systemic inflammation can cause damage to multiple organs, e.g., kidneys, skin, heart, lungs and the nervous system. READ MORE

  3. 3. Growth hormone and the heart in children

    Author : Anders Nygren; Göteborgs universitet; Göteborgs universitet; Gothenburg University; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Growth hormone secretion pattern; Cardiac dimensions; Growth hormone treatment;

    Abstract : Background and Aims: The fact that growth hormone (GH) influences cardiovascular structure and function is well established through both human and animal studies. Despite being secreted in a pulsatile fashion, only the impact of peak GH concentrations on cardiac parameters has previously been reported, and the time-dependency of cardiovascular effects during GH treatment has not been detailed. READ MORE

  4. 4. Genetic Variations in Type 2 Diabetes and Cardiovascular Disease: A Focus on Gene-Lifestyle Interactions and Mendelian Randomization

    Author : George Hindy; Diabetes - kardiovaskulär sjukdom; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Type 2 diabetes; cardiovascular disease; coronary heart disease; metabolic syndrome; genetics; gene-lifestyle interactions; diet; TCF7L2; WNT signaling; chromosome 9p21; Mendelian randomization;

    Abstract : Type 2 diabetes (T2D) and cardiovascular disease (CVD) are highly prevalent complex diseases that result from lifestyle and genetic factors. Gene-lifestyle interactions are also believed to contribute to the etiology of these diseases. READ MORE

  5. 5. The Human Pancreatic Islet Methylome and Its Role in Type 2 Diabetes

    Author : Tasnim Dayeh; Diabetes - epigenetik; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; CpG-SNP; glucagon secretion; insulin secretion; human pancreatic islets; DNA methylation; Epigenetics;

    Abstract : Islet dysfunction is central to the development and progression of type 2 diabetes (T2D). Epigenetic modifications are essential for establishing and maintaining cell identity and function in normal circumstances. Exposure to adverse environmental factors may alter the epigenome, and result in changes of gene expression and the resulting phenotype. READ MORE