Search for dissertations about: "genetic benefits"
Showing result 16 - 20 of 91 swedish dissertations containing the words genetic benefits.
-
16. Pharmacological and genetic modulation of adult neurogenesis in animal models relevant to neuropsychiatric disorders
Abstract : During the past decade, the modulation of adult neurogenesis has been an intensively studied area of neuroscience due to the implications for understanding of physiological mechanisms in the adult brain and the potential clinical applications for neuropsychiatric disorders. This research has resulted in countless discoveries during a relatively short period of time elucidating mechanistic details about where adult neurogenesis takes place, how the process of neurogenesis occurs and how this process can be regulated at several different steps by, not only endogenous mechanisms which normally maintain a homeostasis of adult neurogenesis, but also by exogenous regulation using genetic and pharmacological modulations to manipulate steps of the process. READ MORE
-
17. Towards Precision Medicine: Exploiting Genetic Variation in Tumours by Inferring Multitype Gene Regulatory Networks
Abstract : Precision medicine aims to customize treatment to a patient given measured genetic or other molecular data for diagnostics. In cancer, optimal medical treatment, depends on how far the disease has progressed, type and subtype of cancer and, the individual tumor’s circumstances. READ MORE
-
18. Molecular Investigations of high-risk Mantle Cell Lymphoma : Genetic factors and the impact of the microenvironment
Abstract : Mantle cell lymphoma (MCL) is an aggressive disease, with variable clinical course and heterogenous molecular characteristics. In this thesis, which is based upon six original papers, we aimed to understand MCL deregulations, both at intrinsic and extrinsic levels, to identify companion biomarkers that would allow patient stratification. READ MORE
-
19. Genetic variation in resistance to fungal storage diseases in apple : inoculation-based screening, transcriptomics and biochemistry
Abstract : Apple is one of the economically and culturally most important fruit crops and has many health-related benefits. Apple production is, however, sensitive to several fungal diseases including blue mold, caused by Penicillium expansum. READ MORE
-
20. Windows and blinds selection for enhancing subjective well-being
Abstract : Earlier studies in the context of windows and blinds selection have mostly tried to increase the awareness regarding various effects of windows and blinds selection on subjective well-being, including their effect on visual comfort, thermal comfort, energy consumption and life cycle cost. However, the main problem is the potential conflicts between visual comfort, thermal comfort, energy consumption and life cycle cost. READ MORE
