Search for dissertations about: "genetic causes of multiple sclerosis"

Showing result 1 - 5 of 15 swedish dissertations containing the words genetic causes of multiple sclerosis.

  1. 1. Identification of autoantigens in multiple sclerosis

    Author : Mattias Bronge; Karolinska Institutet; Karolinska Institutet; []
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    Abstract : Multiple sclerosis (MS) is an autoimmune disorder of the central nervous system in which cells from primarily the adaptive immune system infiltrate the brain and spinal cord, leading to inflammation and demyelination. Debuting primarily between 20-40 years of age and with a prevalence in Sweden of ~0. READ MORE

  2. 2. Studies of risk loci in multiple sclerosis

    Author : Magdalena Lindén; Karolinska Institutet; Karolinska Institutet; []
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    Abstract : Multiple sclerosis (MS), a chronic inflammatory disease of the central nervous system, is one of the most common causes of neurological disability among young adults. While the etiology is unknown, an increasing number of environmental and genetic risk factors is being identified. READ MORE

  3. 3. Genetic studies of complex autoimmune disease

    Author : Alexandra Gyllenberg; Karolinska Institutet; Karolinska Institutet; []
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    Abstract : In complex autoimmune diseases, there are both genetic and environmental factors that influence our immune system and contribute to the development of disease. The pathways, interactions and mode of inheritance are difficult to unravel, and many discoveries are yet to be done. READ MORE

  4. 4. From genetic associations to biological implications in multiple sclerosis

    Author : Wangko Lundström; Karolinska Institutet; Karolinska Institutet; []
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    Abstract : Every year, 600 people in Sweden develop MS, making it the second most common cause of disability (after accidents) in young adults. The pathophysiology is characterized by inflammation of the central nervous system and impaired neuronal signaling. READ MORE

  5. 5. Genetic and environmental influences on multiple sclerosis complications and aetiology

    Author : Kelsi Alexandra Smith; Karolinska Institutet; Karolinska Institutet; []
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    Abstract : Multiple sclerosis (MS) is an immune mediated, neurological disease that results in a chronic accumulation of disability over time. Many advances in the understanding, diagnosis and treatment of MS have been made, yet questions surrounding causes and consequences still remain. READ MORE