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Showing result 1 - 5 of 1687 swedish dissertations matching the above criteria.

2. 1. Genetic Determinants of Dyslipidemia

   Author : Tibor V Varga; Genetisk och molekylär epidemiologi; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Genetic epidemiology; Genetic polymorphism; dyslipidaemia; Cholesterol; Triglyceride; Genetic risk; genetic risk score; Single nucleotide polymorphism; Prediction; Gene-environment interactions; Randomized controlled trial; prospective cohort studies; Observational study; GLACIER Study; Diabetes Prevention Program;

   Abstract : Dyslipidemia is a chronic deviation from normal blood lipid levels that can lead to atherosclerosis and other cardiovascular diseases; dyslipidemia and its sequelae are caused by the complex interplay of genetic and environmental factors. Although circulating concentrations of total cholesterol (TC), triglycerides (TG), low-density lipoprotein cholesterol (LDL-C) and high-density lipoprotein cholesterol (LDL-C) have a strong genetic underpinning, not much is known about the genetic factors that affect long-term deteriorations in lipid concentrations. READ MORE

4. 2. Crohn's disease : Studies on epidemiology, twins, aetiological factors and clinical course with special reference to smoking

   Author : Eva Lindberg; Linköpings universitet; []
   Keywords : Crohn s disease; epidemiology; incidence; prevalence; smoking; genetics; twins; dietary antigens; yeast; Saccharomyces cerevisiae; mannan; gliadin; betalactoglobulin; ovalbuntin; MEDICINE; MEDICIN;

   Abstract : In an epidemiological study of the incidence of Crohn's disease in Orebro county during the 25-year period 1963-1987, the mean annual incidence was 6.1/105 inhabitants. During the first five year period the mean incidence was 4.3 but during the following four quinquennia the incidence was stable at around 6. READ MORE

5. 3. Fungal disease dynamics, genetic variation and biodiversity-yield relationships : — a study along a gradient of coffee management in southwestern Ethiopia

   Author : Beyene Zewdie Hailu; Kristoffer Hylander; Ayco J.M Tack; Jacques Avelino; Stockholms universitet; []
   Keywords : NATURVETENSKAP; NATURAL SCIENCES; Armillaria root rot; biodiversity; biodiversity-yield trade-offs; coffee; Coffea arabica; coffee berry disease; coffee leaf rust; coffee wilt disease; coffee yield; genetic composition; genetic diversity; hyperparasite; management intensity gradient; southwestern Ethiopia; Plant Ecology; växtekologi;

   Abstract : Intensification of agricultural systems is a major threat to the associated biodiversity and could also affect the dynamics of pests and pathogens. One such system that is currently under an intensification trajectory is the production of Arabica coffee. READ MORE

6. 4. Psoriatic arthritis: a complex disease : analyses on genetic and serological biomarkers and of comorbidity

   Author : Kristina Juneblad; Gerd-Marie Alenius; Solbritt Rantapää-Dahlqvist; Lars-Erik Kristenssen; Umeå universitet; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Psoriatic Arthritis; genetics; inflammasomes; polymorphisms; biomarkers; disease expression; disease activity; cardiovascular diseases; mortality; epidemiology;

   Abstract : Psoriatic Arthritis (PsA) is a heterogonous inflammatory arthritis associated with psoriasis. The disease leads to inflammation of peripheral joints, axial skeleton and/or enthesites, and can result in severe destruction of affected joints. READ MORE

7. 5. Genetic Studies of Alzheimer's Disease

   Author : Elin Blom; Anna Glaser; Martin Ingelsson; Lars Lannfelt; Jan Hillert; Uppsala universitet; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Alzheimer s disease; Linkage; Affected sib-pairs; APOE; APP duplication; 10q21; 19q13; Wnt signaling; Geriatrics and medical gerontology; Geriatrik och medicinsk gerontologi;

   Abstract : Patients with Alzheimer's disease (AD) often have a family history of the disease, implicating genetics as a major risk factor. Three genes are currently known to cause familial early-onset AD (65 years), only the APOE gene has repeatedly been associated to AD, where the ε4 allele increases disease risk and decreases age at onset. READ MORE