Search for dissertations about: "genetic epidemiology"

Showing result 11 - 15 of 206 swedish dissertations containing the words genetic epidemiology.

2. 11. lnclusion body myositis - Genetic, clinical, and epidemiological aspects

   Author : Ulrika Lindgren; Göteborgs universitet; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; inclusion body myositis; mitochondrial DNA; epidemiology; cytochrome c oxidase; inflammatory myopathy;

   Abstract : The inflammatory myopathy inclusion body myositis (IBM) is characterized by progressive muscle weakness and dysphagia in individuals over 45 years of age. Muscle biopsy shows inflammatory infiltrates, vacuoles with protein accumulation and cytochrome c oxidase (COX)-deficient muscle fibers. READ MORE

4. 12. Genetic variation and prostate cancer : population-based association studies in Sweden

   Author : Sara Lindström; Henrik Grönberg; Fredrik Wiklund; John Todd; Umeå universitet; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Prostate cancer; epidemiology; SRD5A2; ERG; progression; genetics; association studies; polymorphism; haplotype; CDH1; AR; CYP17; Oncology; Onkologi;

   Abstract : Prostate cancer constitutes the most common malignancy and the most common cause of cancer‐related death in Swedish men. A large body of evidence suggests that inherited genetic variants contribute to both development and progression of prostate cancer. READ MORE

5. 13. Molecular epidemiology of streptococcus agalactiae : mobile elements as genetic markers

   Author : Shi-Lu Luan; Mari Norgren; Barbara Spellerberg; Umeå universitet; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Streptococcus agalactiae; group II intron GBSi1 ; multilocus sequence typing; capsular serotype; population structure; Clinical bacteriology; Klinisk bakteriologi;

   Abstract : Streptococcus agalactiae, also designated group B streptococcus (GBS), is a Gram-positive coccus, and it is an important pathogen that causes invasive disease in neonates, pregnant adults, and non-pregnant adults with predisposing conditions. The group II intron GBSi1 is one of the major mobile genetic elements identified in S. agalactiae. READ MORE

6. 14. Fragility fractures in fragile people : epidemiology of the age quake

   Author : Ulrica Bergström; Håkan Jonsson; Ulrika Pettersson; Hans Stenlund; Karl Obrant; Umeå universitet; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Fragility; fractures; elderly; epidemiology; age quake; population based; Vitamin D.; Orthopaedics; Ortopedi; Orthopaedics; ortopedi;

   Abstract : Osteoporosis-related fracture is already today a major public health problem and the number of hip fractures is expected to double to 2030. Sweden has one of the highest hip fracture incidences worldwide. This may be explained by several factors: e.g. READ MORE

7. 15. Osteoarthritis. Epidemiologic and genetic aspects

   Author : Jonas Franklin; Lund Ortopedi; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; body mass index; knee; hip; epidemiology; Osteoarthritis; occupation; hip fracture; inheritance; natural history;

   Abstract : The purpose of this study was to (I) assess the association between body mass index (BMI) and total hip replacement (THR) and total knee replacement (TKR) due to osteoarthritis (OA), (II) assess the association between the mechanical load of work and THR and TKR due to OA, (III) evaluate the natural history of radiographic hip OA with regards to THR and hip fracture, (IV) to determine the prevalence of radiographic OA in patients with hip fracture, and (V) to examine and compare the inheritance patterns of THR for OA and hip fracture. OA was previously regarded as a consequence of the wear and tear the joint is subjected to during one’s lifetime. READ MORE