Search for dissertations about: "genetic linkage"
Showing result 6 - 10 of 291 swedish dissertations containing the words genetic linkage.
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6. Genetic Studies of Alzheimer's Disease
Abstract : Patients with Alzheimer's disease (AD) often have a family history of the disease, implicating genetics as a major risk factor. Three genes are currently known to cause familial early-onset AD (65 years), only the APOE gene has repeatedly been associated to AD, where the ε4 allele increases disease risk and decreases age at onset. READ MORE
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7. Genetic Disequilibria and the Interpretation of Population Genetic Structure in Daphnia
Abstract : Understanding the processes that shape the spatial distribution of genetic variation within species is central to the evolutionary study of diversification and demography. Neutral genetic variation reflects past demographic events as well as current demographic characteristics of populations, and the correct interpretation of genetic data requires that the relative impact of these forces can be identified. READ MORE
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8. Linkage maps in studies of genetic variation - examples from Beta vulgaris
Abstract : Today, most studies of genetic variation utilise molecular markers, making it possible to detect variation at the DNA level. This has greatly facilitated studies of genetic variation in population and evolutionary genetics, systematics and transmission genetics. READ MORE
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9. Mapping genetic diseases in northern Sweden
Abstract : The population of northern Sweden has previously been shown to be well suited for the mapping of monogenic diseases. In this thesis we have tested the hypothesis that this population could also be used for efficient identification of risk genes for common diseases. READ MORE
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10. Genetic investigations of four neurological disorders : From phenotype to mutation
Abstract : More than 5000, more or less rare, genetic diseases are known in man. A genetic disease is in most casesinherited from one generation to the next, and is caused by a change in the genetic code, a mutation. READ MORE