Search for dissertations about: "genetic modelling"

Showing result 1 - 5 of 89 swedish dissertations containing the words genetic modelling.

  2. 1. Of Mice and MYC : Modelling Medulloblastoma

    Author : Oliver Mainwaring; Fredrik J. Swartling; Charles Eberhart; Uppsala universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Medulloblastoma; MYC; Group 3; Cdkn2a; ARF; HSP90; Chromosome 17q; Medicinsk vetenskap; Medical Science; Oncology; Onkologi;

    Abstract : Brain tumours are the leading cause of cancer-related paediatric deaths, with medulloblastoma (MB) being the most common malignant paediatric brain tumour. MB is stratified into four major subgroups – WNT, SHH, Group 3, and Group 4, nomenclature defined by key pathways and drivers involved within each subgroup. READ MORE

  4. 2. Modelling and genetic correction of liver genetic diseases

    Author : Mihaela Zabulica; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : The urea cycle is a set of biochemical reactions that converts highly toxic ammonia into urea for excretion. Deficiencies in any of the genes of the cycle can be life-threatening, with liver transplantation currently being the only definitive treatment. READ MORE

  5. 3. Validated Modelling of Electrochemical Energy Storage Devices

    Author : Niklas Mellgren; Anders Dahlkild; Michael Vynnycky; Jesper Oppelstrup; KTH; []
    Keywords : TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; lithium ion battery; polymer electrolyte fuel cell; modelling; model validation; parameter fitting; Fluid mechanics; Strömningsmekanik;

    Abstract : This thesis aims at formulating and validating models for electrochemical energy storage devices. More specifically, the devices under consideration are lithium ion batteries and polymer electrolyte fuel cells. A model is formulated to describe an experimental cell setup consisting of a LixNi0.8Co0. READ MORE

  6. 4. Modelling and Simulation of Dynamic Behaviour in Crushing Plants

    Author : Gauti Asbjörnsson; Chalmers tekniska högskola; []
    Keywords : TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; Crushing; Dynamic Simulation; Modelling; Screening;

    Abstract : Crushing plants are a vital part in the production of aggregates and metals. Plants are traditionally simulated with a steady-state simulation. With steady-state simulation the plant is simulated until equilibrium is achieved. READ MORE

  7. 5. Simulation of vertical dynamic interaction between railway vehicle and slab track

    Author : Emil Aggestam; Chalmers tekniska högskola; []
    Keywords : TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; transition zones; genetic algorithm; dynamic vehicle–track interaction; Slab track; modelling; ballasteless track;

    Abstract : The usage of slab track for high-speed railway lines has increased in recent decades. In Sweden, the building of new railway lines for higher speed and the selection of track design for such lines are currently being debated. READ MORE