Search for dissertations about: "genetic polymorphisms UGT1A-and MDR1 gene"

Found 1 swedish dissertation containing the words genetic polymorphisms UGT1A-and MDR1 gene.

2. 1. Studies on intrinsic and extrinsic sources of variability in pharmacokinetics and pharmacodynamics

   Author : Johanna Mercke Odeberg; Avdelningen för klinisk kemi och farmakologi; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; toxikologi; pharmacy; pharmacognosy; Pharmacological sciences; Medicin människa och djur ; Medicine human and vertebrates ; genetic polymorphisms UGT1A-and MDR1 gene ; indirect response model; desmopressin; oral lipid based formulations; farmaci; Farmakologi; toxicology; farmakognosi;

   Abstract : Variability in pharmacokinetic and pharmacodynamic parameters between individuals can be due to intrinsic and extrinsic factors. In this thesis three different areas regarding sources of variability have been investigated. 1. Formulation properties as an extrinsic source of variability. READ MORE