Search for dissertations about: "genetic regulation"

Showing result 1 - 5 of 582 swedish dissertations containing the words genetic regulation.

  1. 1. Genetic Information - Values and Rights. The morality of presymptomatic genetic testing

    University dissertation from Göteborg : Göteborg University

    Author : Niklas Juth; Göteborgs universitet.; Gothenburg University.; [2005]
    Keywords : HUMANIORA; HUMANITIES; morality; biomedical ethics; genetic information; genetic testing; presymptomatic; values; rights; autonomy; well-being; justice; genetic counselling; Kantian ethics; authenticity; privacy; confidentiality; insurance;

    Abstract : The focal point of this dissertation is the question of the value of and right to genetic information from presymptomatic genetic testing that may reveal risk of disease. This question is discussed regarding first parties, that is, the person on whom the test is performed, second parties, that is, blood relatives’ of first parties, and third parties, such as insurance companies and employers. READ MORE

  2. 2. Genetic regulation of autoimmune neuroinflammation

    University dissertation from Stockholm : Karolinska Institutet, Department of Medicine

    Author : Kristina Becanovic; Karolinska Institutet.; Karolinska Institutet.; [2003]
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MS; EAE; QTL; gene regulation; linkage analysis;

    Abstract : Multiple sclerosis (MS) is a complex disease characterized by inflammation and demyelination in the central nervous system (CNS), causing neurological deficits. Although there is an increased familial aggregation rate and evidence for a genetic influence on disease susceptibility, environmental factors are also of importance. READ MORE

  3. 3. Platelet monoamine oxidase : From genetic regulation to behavior

    University dissertation from Uppsala : Acta Universitatis Upsaliensis

    Author : Håkan Garpenstrand; Uppsala universitet.; [2000]
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Neurosciences; monoamine oxidase; platelet; personality; CNS; serotonin; dopamine; Neurovetenskap; MEDICINE Dermatology and venerology; clinical genetics; internal medicine Internal medicine Neurology; MEDICIN Dermatologi och venerologi; klinisk genetik; invärtesmedicin Invärtesmedicin Neurologi; medicinsk farmakologi; Medical Pharmacology;

    Abstract : Genetic and environmental factors contribute to the development of personality and vulnerability forpsychiatric disorders. The activity of monoamine oxidase in platelets (trbc-MAO), which is mainlygenetically determined, correlates to personality traits such as sensation-seeking and impulsiveness, andlow trbc-MAO activity is more common in patients with type 2 alcoholism. READ MORE

  4. 4. Cytochrome P-450 in Drosophila melanogaster : activity, genetic variation and regulation

    University dissertation from Stockholm : Stockholm University

    Author : Inger Porsch-Hällström; Stockholms universitet.; [1984]

    Abstract : The cytochrome P-450 enzyme system in the fruit fly, Drosophila melanogaster, was shown to be inducible, to consist of several isozymes and to have the capacity to metabolize a variety of substrates, thus resembling the corresponding mammalian system. These similarities strengthens the value of Drosophila test systems for the detection of indirect carcinogens and mutagens. READ MORE

  5. 5. Lifestyle and glycaemic control before and after the onset of type 2 diabetes

    University dissertation from Lund University: Faculty of Medicine

    Author : Robert Koivula; Lund University.; Lunds universitet.; Lund University.; Lunds universitet.; [2016]
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Type 2 Diabetes; Prediabetes; Obesity; Beta-cell Function; Insulin Sensitivity; Physical Activity; Exercise; Diet; Lifestyle; Ectopic Fat; Genetic Epidemiology; Genetic Risk; Biomarker; Precision Medicine;

    Abstract : Type 2 diabetes (T2D) is a complex disease with widespread physiological insults to the regulation of metabolic homeostasis, above all glycaemic regulation. The pathogenesis of T2D and its progression is broadly understood to be through a gradual decrease in peripheral insulin sensitivity, a compensatory rise in insulin secretion, and a gradual decline in beta-cell function, resulting in glycaemic dysregulation and eventual T2D. READ MORE