Search for dissertations about: "genetic regulation"

Showing result 6 - 10 of 674 swedish dissertations containing the words genetic regulation.

  2. 6. Genetic and immunological regulation of neuroinflammation

    Author : Mélanie Thessén Hedreul; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : Multiple Sclerosis (MS) affects young adults and is characterized by chronic inflammation and demyelination in the central nervous system that leads to progressive worsening of disease. The cause of MS is incompletely understood and there is a need for more specific and effective treatments. READ MORE

  4. 7. Small RNAs, Big Consequences : Post-transcriptional Regulation and Adaptive Immunity in Bacteria

    Author : Mirthe Hoekzema; Gerhart E. H. Wagner; Magnus Lundgren; Kai Papenfort; Uppsala universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; small RNA; sRNA; non-coding RNA; Hfq; gene regulation; post-transcriptional regulation; biofilm; OmrA; OmrB; toxin-antitoxin; TisB; IstR-1; Persisters; CRISPR-Cas; CRISPR-Cas adaptation reporter; Escherichia coli; Biologi med inriktning mot mikrobiologi; Biology with specialization in Microbiology;

    Abstract : It is nowadays widely accepted that non-coding RNAs play important roles in post-transcriptional regulation of genes in all kingdoms of life. In bacteria, the largest group of RNA regulators are the small RNAs (sRNAs). READ MORE

  5. 8. Gene regulation models of viral genetic switches

    Author : Maria Werner; Erik Aurell; Michael Hörnquist; KTH; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; Biological physics; Biologisk fysik;

    Abstract : The recent decades of research in molecular biology have resulted in break-throughs concerning our knowledge of the genetic code, protein structures and functions of the different cellular components. With this new information follows an increased interest in constructing computational models of the biological systems. READ MORE

  6. 9. Genetic regulation of autoimmunity in experimental neuroinflammation

    Author : Sevasti Flytzani; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : Multiple sclerosis (MS) is a chronic inflammatory disease that affects the central nervous system causing axonal demyelination and leads to significant disabilities. MS affects mainly young adults and incidence of disease in Sweden is around 600 new cases/year. READ MORE

  7. 10. Genetic regulation of neuroinflammation : a translational approach

    Author : Johan Öckinger; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : Multiple sclerosis (MS) is a chronic inflammatory disease of the central nervous system (CNS), causing demyelination and axonal damage. As other complex diseases with an inflammatory or autoimmune component, MHC is a strong regulator of the disease and acts in concert with multiple nonMHC genes and environmental factors. READ MORE