Search for dissertations about: "genetic-markers"

Showing result 21 - 25 of 121 swedish dissertations containing the word genetic-markers.

  2. 21. Dispersal, inbreeding and fitness in natural populations

    Author : Bengt Hansson; MEMEG; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; immigration; inbreeding; inbreeding depression; heterozygosity; microsatellite; great reed warbler; bird; Djurekologi; Animal ecology; philopatry; heritability; founder event; dispersal; bottleneck;

    Abstract : To evaluate how inbreeding affects the viability of small populations, it is crucial to determine what constitutes a population (i.e., the number of breeders in local patches and the degree of dispersal), and also to estimate the reproductive consequences of philopatry and emigration. READ MORE

  4. 22. Computational statistical methods for genotyping biallelic DNA markers from pooled experiments

    Author : Camille Clouard; Carl Nettelblad; Lars Rönnegård; Uppsala universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES;

    Abstract : The information conveyed by genetic markers such as Single Nucleotide Polymorphisms (SNPs) has been widely used in biomedical research for studying human diseases, but also increasingly in agriculture by plant and animal breeders for selection purposes. Specific identified markers can act as a genetic signature that is correlated to certain characteristics in a living organism, e. READ MORE

  5. 23. Sequence evolution in a chromosomal region of Arabidopsis thaliana

    Author : Jenny Hagenblad; Biologiska institutionen; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; Växtgenetik; Plant genetics; flowering time; mapping; polymorphism; Linkage disequilibrium; Arabidopsis thaliana;

    Abstract : Recently there has been a lot of interest in the use of liknage disequilibrium (LD) in genome wide scans for new genes, so called association mapping. Of crucial importance to a genome wide scan for associations between genetic markers and the trait of interest is the extent of LD, as it determines both how closely a trait can be mapped and also how many markers is needed to map it. READ MORE

  6. 24. Genomics and bioinformatics strategies in the study of aging and Alzheimer disease

    Author : Mun-Gwan Hong; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : To understand complex phenotypes, medical research has evolved from the study of single genes and proteins to approaches that encompass more comprehensive catalogues of molecules. Among the more widely used are genome-wide expression and high-throughput genotyping, the latter primarily making use of single nucleotide polymorphisms (SNPs) in what has been termed genome-wide association studies (GWAS). READ MORE

  7. 25. Statistical methodology for testing genetic association in family-based studies

    Author : Gudrun Jonasdottir; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : This thesis is concerned with family-based studies of association between genetic markers and binary traits. A special point of interest in family-based association studies is to separate the within family correlation and the genetic effect common among all families in the study. READ MORE