Search for dissertations about: "genetically engineered T cells"
Showing result 1 - 5 of 9 swedish dissertations containing the words genetically engineered T cells.
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1. The Multiple Faces of Genetically-Modified T Cells : Potential Applications in Therapy
Abstract : In this PhD thesis the potential of T-cells as therapy for disease are explored. The applications of genetically modified T-cells for treatment of cancer and autoimmune disease; the functionality and optimal activation of T-cells are discussed. READ MORE
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2. Characterization and targeting of leukemia propagating cells
Abstract : Patients with hematopoietic malignancies have a large, unmet medical need. Allogeneic hematopoietic stem cell transplantation remains the only curative option, but many patients are not eligible for such treatment. READ MORE
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3. CNS-Targeted Cell Therapy for Multiple Sclerosis
Abstract : Multiple sclerosis (MS) is an autoimmune disorder of the central nervous system (CNS). In the current thesis, we have preformed an immunological investigation of patients with MS and developed an immunosuppressive cell therapy that could be beneficial for these patients. READ MORE
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4. Immunohistochemical study of rats receiving peripheral immunization with IFNg transfected glioma cells
Abstract : Malignant glioma is, with rare exceptions in younger adults, an uncurable brain tumor, as very few survive more than 1-2 years after diagnosis. Despite advances in recent years, current treatments such as surgery, radiotherapy and chemotherapy only prolongs the life of the patients. READ MORE
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5. Human immune responses to SARS-Cov-2 and influenza A virus infection : from myeloid-derived suppressor cells and T cell functions to antibody responses
Abstract : Acute respiratory viral infections are the most frequent reason for medical consultations in the world. They cause substantial illness and death every year, especially in young children, the immunocompromised and the elderly, with a large span of disease severity ranging from mild to fatal. READ MORE