Search for dissertations about: "genetics of psoriasis"

Showing result 1 - 5 of 7 swedish dissertations containing the words genetics of psoriasis.

  2. 1. Population genetic studies of psoriasis

    Author : Annica Inerot; Göteborgs universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; psoriasis; population genetics; age of onset; family studies; associated diseases; clinical examination; arthritis; HLA-Cw6;

    Abstract : Psoriasis is a genetically determined, common skin disease affecting about 3 % of the population. The inheritance pattern has earlier been unclear. In collaboration with the Swedish Psoriasis Association, we have collected information on the occurrence of psoriasis in the families of 11,366 members of the Association. READ MORE

  4. 2. The Genetics of Systemic Lupus Erythematosus : The Specificity of IRF5 to SLE

    Author : MV Prasad Linga Reddy; Marta Alarcön Riquelme; Dan Holmberg; Uppsala universitet; []
    Keywords : Molecular genetics; Systemic lupus erythematosus; Interferon regulatory factor 5; Transmission-Disequilibrium Test; Family-based association test; Linkage Disequilibrium; Hardy-Weinberg equilibrium; Genetik;

    Abstract : The breakdown of self-tolerance is the main driving force behind susceptibility to SLE. When this occurs, T and B cells are activated in an uncontrolled manner and produce autoantibodies against self fragmented DNA, RNA and sometimes other parts of the cell such as cardiolipin, phosphatidylserine, etc. READ MORE

  5. 3. Genetic susceptibility to psoriasis in Sweden

    Author : Fredrik Enlund; Göteborgs universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; CD80; CD86; joint complaints; linkage analysis; NPL; psoriasis; TDT; chromosome region 3q21;

    Abstract : A common skin disease affecting about 2-3% of the population, psoriasis has an inheritance pattern that is unclear, but most probably many genes are involved in its pathogenesis. Other studies have suggested many susceptibility regions in the genome, but as yet independent studies have replicated only some of these regions located on chromosome 1q, 6p and 17q. READ MORE

  6. 4. Psoriatic arthritis: a complex disease : analyses on genetic and serological biomarkers and of comorbidity

    Author : Kristina Juneblad; Gerd-Marie Alenius; Solbritt Rantapää-Dahlqvist; Lars-Erik Kristenssen; Umeå universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Psoriatic Arthritis; genetics; inflammasomes; polymorphisms; biomarkers; disease expression; disease activity; cardiovascular diseases; mortality; epidemiology;

    Abstract : Psoriatic Arthritis (PsA) is a heterogonous inflammatory arthritis associated with psoriasis. The disease leads to inflammation of peripheral joints, axial skeleton and/or enthesites, and can result in severe destruction of affected joints. READ MORE

  7. 5. A Clinical and Genetic Study of Psoriatic Arthritis

    Author : Gerd-Marie Alenius; Umeå universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Public health; Psoriatic arthritis; prevalence; inflammatory manifestations; genetic loci; HLA; TNFB; Folkhälsomedicin; Public health medicine research areas; Folkhälsomedicinska forskningsområden; Clinical Genetics; klinisk genetik;

    Abstract : Psoriatic arthritis (PsA) is an inflammatory joint disease associated with psoriasis. PsA has a heterogeneous pattern, expressed by different manifestations such as mild mono-oligoarthritis or very severe, erosive and destructive polyarthritis. Measurable inflammatory activity is not always prominent. READ MORE