Search for dissertations about: "genital herpes"

Showing result 1 - 5 of 22 swedish dissertations containing the words genital herpes.

  1. 1. Development of novel immunization approaches to generate immunity in the female genital tract with special reference to genital herpes

    Author : Sara Tengvall; Göteborgs universitet; []
    Keywords : female genital tract immunity; genital herpes; mucosal adjuvant; TLR; MyD88; CpG ODN;

    Abstract : Development of mucosal vaccines for inducing immunity in the female reproductive tract would have profound implications for the prevention of sexually transmitted diseases. Despite numerous efforts, no such vaccines are currently available for human use. READ MORE

  2. 2. Herpes simplex virus infection: epidemiological aspects and analysis of the type-specific antibody response

    Author : Petra Tunbäck; Göteborgs universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; herpes simplex virus; first episode genital herpes; seroepidemiology type-specific antibody-response; glycoprotein G-1; epitope-mapping;

    Abstract : Herpes simplex virus type 1 (HSV-1) and type 2 (HSV-2) are ubiquitous viruses, often leading to asymptomatic infections in humans. However, different clinical presentations can be seen including recurrent oral or genital lesions, meningitis and neonatal herpes. READ MORE

  3. 3. Innate and adaptive immunity in genital HSV-2 infection: Implications for vaccine development

    Author : Ali M Harandi; Göteborgs universitet; []
    Keywords : genital herpes infection; natural antibody; CD4 T cells; CD8 T cells; IFN-g; IL-12; IL-18; CC chemokines; dendritic cells.;

    Abstract : Herpes simplex virus type 2 (HSV-2) is a sexually transmitted pathogen that infects the genital tract mucosa and is the most common case of genital ulcers in humans. Despite numerous studies, little is known about the mechanisms involved in immune protection and no anti-herpes vaccine has been developed to date. READ MORE

  4. 4. Mucosal adjuvants and their mode of action in the female genital tract

    Author : Madelene Lindqvist; Göteborgs universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; immunology; mucosal adjuvants; genital tract; vaccine; HSV-2; mouse; alpha-galactosylceramid; CpG ODN; proteoliposome-derived cochleate; inflammation; bioinformatics;

    Abstract : Sexually transmitted infections (STIs) cause a socioeconomic burden, morbidity and even mortality in a large part of the human population all over the world today. One of the most common genital ulcerative diseases is caused by herpes simplex virus type 2 with over 536 million people infected world-wide. READ MORE

  5. 5. Immunization approaches and molecular signatures for mucosal immunity to primary and recurrent genital herpes

    Author : Josefine Persson; Göteborgs universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Immunologi;

    Abstract : Genital herpes is most commonly caused by herpes simplex virus type 2 (HSV-2), and is a prevalent sexually transmitted infection worldwide. Despite numerous efforts, there is currently no licensed vaccine against the disease. READ MORE