Search for dissertations about: "genome reduction"

Showing result 1 - 5 of 71 swedish dissertations containing the words genome reduction.

  1. 1. Dynamics of the Bacterial Genome Rates and Mechanisms of Mutation

    University dissertation from Uppsala : Acta Universitatis Upsaliensis

    Author : Sanna Koskiniemi; Uppsala universitet.; [2010]
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; bacteria; bacterial evolution; genome reduction; gene loss; serial passage; DNA homology; tranlesion DNA polymerase; stress; MEDICINE Microbiology; immunology; infectious diseases Microbiology; MEDICIN Mikrobiologi; immunologi; infektionssjukdomar Mikrobiologi; MEDICINE Microbiology; immunology; infectious diseases Microbiology Bacteriology; MEDICIN Mikrobiologi; immunologi; infektionssjukdomar Mikrobiologi Bakteriologi; Evolutionary Genetics; Evolutionär genetik; Mikrobiologi; Microbiology;

    Abstract : Bacterial chromosomes are highly dynamic, continuously changing with respect to gene content and size via a number of processes, including deletions that result in gene loss. How deletions form and at what rates has been the focus of this thesis. In paper II we investigated how chromosomal location affects chromosomal deletion rates in S. READ MORE

  2. 2. Lifestyle and Genome Evolution in Vector-Borne Bacteria A Comparison of Three Bartonella Species

    University dissertation from Uppsala : Acta Universitatis Upsaliensis

    Author : Anna Carolin Frank; Uppsala universitet.; [2005]
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; Biology; Bartonella; evolution; host-restriction; vector-borne; horizontal gene transfer; genome reduction; alpha-proteobacteria; Type-IV secretion; Biologi; NATURAL SCIENCES Biology; NATURVETENSKAP Biologi;

    Abstract : Bacterial genomes provide records of the molecular processes associated with emergence and evolution of different bacterial lifestyles. This thesis is based on whole-genome comparisons within the genus Bartonella, an excellent model system for studies of host- and vector-specificity and infection outcome in animal-associated bacteria. READ MORE

  3. 3. Dynamics and Mechanisms of Adaptive Evolution in Bacteria

    University dissertation from Uppsala : Acta Universitatis Upsaliensis

    Author : Song Sun; Uppsala universitet.; [2012]
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; adaptive evolution; mutation; genome rearrangements; antibiotic resistance; gene amplification; genome reduction; directed evolution; Biologi med inriktning mot mikrobiologi; Biology with specialization in Microbiology;

    Abstract : Determining the properties of mutations is fundamental to understanding the mechanisms of adaptive evolution. The major goal of this thesis is to investigate the mechanisms of bacterial adaptation to new environments using experimental evolution. READ MORE

  4. 4. The genetic composition and diversity of Francisella tularensis

    University dissertation from Umeå : Klinisk mikrobiologi

    Author : Pär Larsson; Umeå universitet.; [2007]
    Keywords : Microbiology; tularemia; genotyping; evolution; microarray; genome sequencing; virulence; genome reduction; Mikrobiologi; Francisella tularensis; klinisk bakteriologi; Clinical Bacteriology;

    Abstract : Francisella tularensis is the causative agent of the debilitating, sometimes fatal zoonotic disease tularemia. To date, little information has been available on the genetic makeup of this pathogen, its evolution, and the genetic differences which characterize subspecific lineages. These are the main areas addressed in this thesis. READ MORE

  5. 5. Technologies for Single Cell Genome Analysis

    University dissertation from Stockholm : KTH Royal Institute of Technology

    Author : Erik Borgström; KTH.; [2016]
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; DNA; sequencing; single molecule; single cell; whole genome amplification; exome sequencing; emulsions; barcoding; phasin; Biotechnology; Bioteknologi;

    Abstract : During the last decade high throughput DNA sequencing of single cells has evolved from an idea to one of the most high profile fields of research. Much of this development has been possible due to the dramatic reduction in costs for massively parallel sequencing. READ MORE