Search for dissertations about: "genome reduction"

Showing result 6 - 10 of 83 swedish dissertations containing the words genome reduction.

  2. 6. Dimension Reduction and Signal Decomposition for Genotype–Phenotype Relations

    Author : Rasmus Perby Henningsson; Matematik LTH; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; Matematik; Bioinformatik; Dimensionsreduktion; Computational mathematics; Bioinformatics; Dimension reduction;

    Abstract : Over the last few decades, DNA sequencing has developed from costing billions of dollars to get the complete sequence of the human genome, to being a routine procedure performed in labs all around the world. This has transformed the field of experimental biology since measurements can be done at a level of detail that was not possible before. READ MORE

  4. 7. Simplicity within Complexity : Understanding dynamics of cellular networks by model reduction

    Author : Olivia Eriksson; Jesper Tegnér; Arne Elofsson; Yishao Zhou; Stefan Bornholdt; Stockholms universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; model reduction; cellular networks; dynamical modules; delayed piecewise linear; systems biology; Biochemistry; Biokemi; biokemi; Biochemistry;

    Abstract : Cellular networks composed of interactions between genes, proteins and metabolites, determines the behavioural repertoire of the cell. Recent developments in high-throughput experimental techniques and computational methods allow static descriptions of these networks on a genome scale. READ MORE

  5. 8. Nonlinear dimensionality reduction of gene expression data

    Author : Jens Nilsson; Matematik LTH; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; Gene expression; Manifold learning; Nonlinear dimensionality reduction; Microarray;

    Abstract : Using microarray measurements techniques, it is possible to measure the activity of genes simultaneously across the whole genome. Since genes influence each others activity levels through complex regulatory networks, such gene expression measurements are state samples of a dynamical system. READ MORE

  6. 9. Mapping the Rickettsia prowazekii genome

    Author : Alireza Zomorodipour; Uppsala universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; Molecular biology; Molekylärbiologi; Molecular biology; Molekylärbiologi; molekylärbiologi; Molecular Biology;

    Abstract : Rickettsia prowazekii is a member of alpha proteobacteria and the etiologic agent of epidemictyphus. Besides its pathogenicity as an obligate intracellular parasite it has been considered as amodel organism in a variety of studies.We have established a collection of overlapping clones, covering nearly the complete R.prowazekii genome. READ MORE

  7. 10. Evolution of symbiotic lineages and the origin of new traits

    Author : Daniel Tamarit; Siv G. E. Andersson; Lisa Klasson; Amparo Latorre; Julian Parkhill; Uppsala universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; symbiosis; host-association; Lactobacillus; Bifidobacterium; Rhizobiales; Bartonella; honeybees; ants; codon usage bias; genome architecture; genome organization; gene transfer agent; evolutionary genomics; comparative genomics; Biologi med inriktning mot molekylär evolution; Biology with specialization in Molecular Evolution; Biology with specialization in Evolutionary Genetics; Biologi med inriktning mot evolutionär genetik; Biologi med inriktning mot mikrobiologi; Biology with specialization in Microbiology;

    Abstract : This thesis focuses on the genomic study of symbionts of two different groups of hymenopterans: bees and ants. Both groups of insects have major ecological impact, and investigating their microbiomes increases our understanding of their health, diversity and evolution. READ MORE