Search for dissertations about: "genome stability"

Showing result 1 - 5 of 83 swedish dissertations containing the words genome stability.

  1. 1. The Smc5/6 complex : the mysterious guardian of genome stability

    University dissertation from Stockholm : Karolinska Institutet, Dept of Cell and Molecular Biology

    Author : Davide G. Berta; Karolinska Institutet.; Karolinska Institutet.; [2016]
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES;

    Abstract : An intricate network of proteins ensures the faithful transmission of genetic information through cell generations. The Structural Maintenance of Chromosomes (SMC) protein complex family plays a pivotal role in maintaining genome stability. READ MORE

  2. 2. Regulation of ribonucleotide reductase and the role of dNTP pools in genomic stability in yeast Saccharomyces cerevisiae

    University dissertation from Umeå : Umeå universitet

    Author : Olga Tsaponina; Umeå universitet.; [2011]
    Keywords : ribonucleotide reductase; dNTP; genome stability;

    Abstract : Every living organism is programmed to reproduce and to pass genetic information to descendants. The information has to be carefully copied and accurately transferred to the next generation.  Therefore organisms have developed the network of conserved mechanisms to survey the protection and precise transfer of the genetic information. READ MORE

  3. 3. Chromatin remodeling and dna topology in transcription and genome stability

    University dissertation from Stockholm : Karolinska Institutet, Dept of Biosciences and Nutrition

    Author : Jenna Persson; Karolinska Institutet.; Karolinska Institutet.; [2013]
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES;

    Abstract : Eukaryotic DNA is wrapped around histone proteins to form nucleosomes, the fundamental repeati ng unit of chromatin. DNA packaging into chromatin both solves and creates problems. It allows the centimeters, or even meters, of DNA that constitute a eukaryotic genome to fit inside a micrometer - scale cell nucleus. READ MORE

  4. 4. Mitotic failure and genome stability in benign, premalignant and malignant human tissues

    University dissertation from Stockholm : Karolinska Institutet, false

    Author : Rüdiger G. Steinbeck; Karolinska Institutet.; Karolinska Institutet.; [1998]
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; aneuploidy; CDF; clonal selection; DNA content; image microphotometry; interphase; microsection; nondisjunction; unbalanced telophase;

    Abstract : Mitotic failure may occur throughout the human lifespan. Individual nuclear mistakes will escape detection within the mass of somatic cells. The probability of nondetection increases with progression in development. READ MORE

  5. 5. Genome Evolution in Maternally Inherited Insect Endosymbionts

    University dissertation from Uppsala : Acta Universitatis Upsaliensis

    Author : Lisa Klasson; Uppsala universitet.; [2005]
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; Biology; Biologi; NATURAL SCIENCES Biology; NATURVETENSKAP Biologi;

    Abstract : Symbiosis is a widely common phenomenon in nature and has undoubtedly contributed to the evolution of all organisms on earth. Symbiotic associations can be of varying character, such as parasitic or mutualistic, but all imply a close relationship. READ MORE