Search for dissertations about: "genome stability"

Showing result 21 - 25 of 113 swedish dissertations containing the words genome stability.

  2. 21. Identification of protein signatures of genomic stability/instability in epithelial cancers

    Author : Timo Gemoll; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : Aneuploidy is a consistent genetic alteration of the cancer genome. At early steps in the sequence of malignant transformation during human tumorigenesis, chromosomal aneuploidies can be the first detectable genetic aberrations found. READ MORE

  4. 22. Interaction of the genome maintenance proteins of oncogeneic herpesviruses with cellular chromatin

    Author : Muhammad Nouman Mughal; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : The Epstein-Barr virus (EBV) nuclear antigen (EBNA)-1 is the only viral protein expressed in all virus-infected cells and EBV-associated malignancies. Similar to the genome maintenance proteins (GMPs) of other gamma-herpesviruses, EBNA1 binds to both viral and cellular DNA and controls the replication and transcription of the viral genome. READ MORE

  5. 23. Hydrogen Production by Caldicellulosiruptor species: The Organism and the Metabolism

    Author : Ahmad Zeidan; Teknisk mikrobiologi; []
    Keywords : TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; Extreme thermophile; Caldicellulosiruptor; Biohydrogen; Co-culture; Coexistence; Hydrogen tolerance; Genome-scale reconstruction; In silico; Flux balance analysis;

    Abstract : Hydrogen holds a great promise as an efficient and clean future energy carrier due to its high energy density and lack of pollutant generation. Anaerobic degradation of organic substrates by heterotrophic microorganisms enables the production of hydrogen from a wide spectrum of agricultural feedstock and waste products. READ MORE

  6. 24. Improving cyanobacteria productivity: From theory to assay

    Author : Kiyan Shabestary; Elton P. Hudson; Daniel Ducat; KTH; []
    Keywords : TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; metabolic engineering; growth-coupling; growth-arrest; cyanobacteria; CRISPRi; CRISPRi library; flux balance analysis; genome-scale model; butanol; lactate; isoprene; Bioteknologi; Biotechnology;

    Abstract : Bio-based production of biochemicals and biofuels holds great promises for the transition towards a more sustainable society. With increasing levels of carbon dioxide (CO2) in the atmosphere, cyanobacteria stand apart as natural catalysts directly converting CO2 and light to product. READ MORE

  7. 25. RNA-based mechanisms of chromatin and gene regulation

    Author : Jordi Planells Rodrigo; Neus Visa; Simon Elsässer; Stockholms universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; Gene regulation; chromatin; non-coding RNAs; genome-wide studies; Drosophila melanogaster; ADAR3; molekylär biovetenskap; Molecular Bioscience;

    Abstract : Cells regulate gene expression in a particular spatio-temporal manner by executing specific transcriptional programs. The different transcriptional programs allow the generation of the different cell types in multicellular organisms and mediate particular cellular responses to external cues such as viral infections. READ MORE