Search for dissertations about: "genome structure"

Showing result 1 - 5 of 289 swedish dissertations containing the words genome structure.

  2. 1. Guardians of the genome : Connecting chromatin structure and genome integrity in Saccharomyces cerevisiae

    Author : Stefanie Lena Bauer; Stefan U. Åström; Brian Luke; Stockholms universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; molekylär biovetenskap; Molecular Bioscience;

    Abstract : Branched DNA structures arise during recombination and during other DNA repair processes such as repair of stalled replication forks. One branched structure, the Holliday Junction (HJ), is a four-way junction that can connect sister chromatids or homologous chromosomes. We show a physical interaction between the HJ-cleaving enzyme Yen1 and Uls1. READ MORE

  4. 2. Borrelia channel-forming proteins : structure and function

    Author : Ignas Bunikis; Sven Bergström; Steven Norris; Umeå universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Borrelia; Lume disease; relapsing fever; BesC; drug efflux; DipA; P66; porins; Molecular biology; Molekylärbiologi; molekylärbiologi; Molecular Biology;

    Abstract : Borrelia is a Gram-negative, corkscrew-shaped bacterium transmitted by infected ticks or lice. Borreliae are subdivided into pathogens of two diseases: Lyme disease, caused mainly by B. burgdorferi, B. afzelii and B. READ MORE

  5. 3. Rates and patterns of genome evolution in Lepidoptera

    Author : Karin Näsvall; Niclas Backström; Simon Martin; Uppsala universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; Chromosomal rearrangements; karyotype evolution; recombination rate; Lepidoptera; genome structure; molecular evolution; Biology with specialization in Evolutionary Genetics; Biologi med inriktning mot evolutionär genetik;

    Abstract : The evolutionary consequences of genome restructuring and chromosomal rearrangements can be significant, but the underlying mechanisms are poorly understood. This thesis explores the relationships between genome restructuring, recombination, and maintenance of genetic diversity in different butterfly species. READ MORE

  6. 4. Classification, Evolution, Pharmacology and Structure of G protein-coupled Receptors

    Author : Malin C Lagerström; Helgi B. Schiöth; Robert Fredriksson; Anthony J. Harmar; Uppsala universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Pharmacology; Classification; Structure; Pharmacology; Evolution; G protein-coupled receptor; Farmakologi; Pharmacological research; Farmakologisk forskning;

    Abstract : G protein-coupled receptors (GPCR) are integral membrane proteins with seven α-helices that translate a remarkable diversity of signals into cellular responses. The superfamily of GPCRs is among the largest and most diverse protein families in vertebrates. READ MORE

  7. 5. Phylogeny and topological incongruence in the Rubioideae (Rubiaceae)

    Author : Olle Thureborn; Catarina Rydin; Sylvain G. Razafimandimbison; Niklas Wikström; Michael D. Pirie; Stockholms universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; Anthospermeae; cytonuclear discordance; gene trees; incomplete lineage sorting; incongruence; mitochondrial genome; nuclear genome; phylogenomics; phylogeny; plastid genome; Rubiaceae; Rubioideae; species trees; Plant Systematics; växtsystematik;

    Abstract : The work with this thesis has focused on evolutionary relationships in the Rubioideae, the most species-rich subfamily of the large and diverse coffee family (Rubiaceae). Despite considerable efforts during the last decades, uncertainty regarding several relationships in this group has remained, either as a result of unconvincing statistic support, incongruent results, or insufficient taxon sampling. READ MORE