Search for dissertations about: "genome virus"

Showing result 1 - 5 of 179 swedish dissertations containing the words genome virus.

  1. 1. Influenza A Virus : Spatial analysis of influenza genome trafficking and the evolution of the neuraminidase protein

    Author : Dan Dou; Robert Daniels; Martin Schwemmle; Stockholms universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; Influenza A virus; IAV; neuraminidase; NA; IAV genome trafficking; viral entry; viral replication; co-infection; antigenic drift; antigenic shift; NA assembly; transmembrane domain; evolution; Biochemistry; biokemi;

    Abstract : Influenza A viruses (IAVs) are a common infectious agent that seasonally circulates within the human population that causes mild to severe acute respiratory infections. The severity of the infection is often related to how the virus has evolved with respect to the pre-existing immunity in the population. READ MORE

  2. 2. Ljungan Virus Replication in Cell Culture

    Author : Jens-Ola Ekström; Kjell Edman; Glyn Stanway; Högskolan i Kalmar; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Ljungan virus; picornavirus; parechovirus; 5 - RACE; 5 -end; infectious cDNA clone; real time PCR; virus purification; virion stability; disinfection; aphthovirus-like 2A; Virology; Virologi; Mikrobiologi; Microbiology;

    Abstract : Ljungan virus (LV) is a recently identified picornavirus of the genus Parechovirus. LV has been isolated from voles trapped in Sweden and also in the United States. LV infected small rodents may suffer from diabetes type 1 and type 2 like symptoms, myocarditis and encephalitis. READ MORE

  3. 3. Exploring the Molecular Dynamics of Proteins and Viruses

    Author : Daniel Larsson; David van der Spoel; Modesto Orozco; Uppsala universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; molecular dynamics; virus dynamics; capsid dissolution; satellite tobacco necrosis virus; satellite tobacco mosaic virus; virus genome structure; gas phase protein structure; water layer; micelle embedded protein; membrane protein; Chemistry with specialization in Biophysics; Kemi med inriktning mot biofysik;

    Abstract : Knowledge about structure and dynamics of the important biological macromolecules — proteins, nucleic acids, lipids and sugars — helps to understand their function. Atomic-resolution structures of macromolecules are routinely captured with X-ray crystallography and other techniques. READ MORE

  4. 4. Viperin vs. tick-borne encephalitis virus : mechanism of a potent antiviral protein

    Author : Kirstin Vonderstein; Anna Överby Wernstedt; Magnus Evander; Sonja Best; Umeå universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; Tick-borne encephalitis virus; TBEV; type-I interferon; IFN; Interferon-stimulated gene; ISG; viperin; GBF1; CIAO1; antiviral protein; genome replication; particle release; capsid;

    Abstract : Tick-borne encephalitis virus (TBEV) is a very important virus medically, causing mild or severe encephalitis often with long-lasting sequelae. Treatment of tick-borne encephalitis is limited to supportive care, and antiviral drugs are much needed.The type-I interferon (IFN) system is the first line of host defense against many viruses. READ MORE

  5. 5. Biology of a small RNA virus that infects Drosophila melanogaster

    Author : Sajna Anand Sadanandan; Dan Hultmark; Francis Jiggins; Umeå universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Nora virus; Drosophila melanogaster; virus biology; host-pathogen interaction; molekylärbiologi; Molecular Biology;

    Abstract : Drosophila melanogaster has been extensively used as a model organism to study diverse facets of biology, including host-pathogen interactions and the basic biology of its pathogens. I have used the fruit fly as a model to study elementary aspects of Nora virus biology, such as the role of the different proteins encoded by the virus genome. READ MORE