Search for dissertations about: "genome-scale model"
Showing result 1 - 5 of 30 swedish dissertations containing the words genome-scale model.
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1. Utilization of single-cell RNA-Seq and genome-scale modeling for investigating cancer metabolism
Abstract : Cancer remains a leading cause of death worldwide, and its dysregulated metabolism is a promising target for therapy. However, metabolism is complex to study – the metabolism of a cell involves the interplay of thousands of chemical reactions that are combined in different ways across tissues and cell types. READ MORE
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2. Modeling human gut microbiota: from steady states to dynamic systems
Abstract : Human gut microbes are an essential part of human sub-microscopic systems and involved in many critical biological processes such as Type 2 diabetes (T2D) and osteoporosis. However, the underlying mechanisms are unclear. READ MORE
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3. Improving cyanobacteria productivity: From theory to assay
Abstract : Bio-based production of biochemicals and biofuels holds great promises for the transition towards a more sustainable society. With increasing levels of carbon dioxide (CO2) in the atmosphere, cyanobacteria stand apart as natural catalysts directly converting CO2 and light to product. READ MORE
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4. Systems biology of protein synthesis and secretion in yeast
Abstract : Protein synthesis and secretion is a vital process to maintain cell function. As it demands numerous building blocks, cofactors and chaperones generated from metabolism and translation, the process is intertwined with metabolic and regulatory networks. READ MORE
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5. A systems biology understanding of protein constraints in the metabolism of budding yeasts
Abstract : Fermentation technologies, such as bread making and production of alcoholic beverages, have been crucial for development of humanity throughout history. Saccharomyces cerevisiae provides a natural platform for this, due to its capability to transform sugars into ethanol. READ MORE